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Barkha P Patel, MSc |
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EDUCATION 2009 - 2013 Doctor of Philosophy (PhD. Candidate) Department of Nutritional Sciences, Faculty of Medicine University of Toronto, Toronto, ON Thesis: Interaction of environmental and physiological determinants of food intake control in children. 2006 – 2008 Master of Science School of Kinesiology and Health Science, Faculty of Health York University, Toronto, ON Thesis: The effects of long-term caloric restriction on molecular outcome measures in the Cu/Zn-SOD mutant G93A mouse, an animal model of amyotrophic lateral sclerosis (ALS). 2002 – 2006 Honours Bachelor of Science Honours Biology, Minor in English McMaster University, Hamilton, ON Fourth Year Independent Study: Long-term caloric restriction increases malondialdehyde in the red and white gastrocnemius muscle in the Cu/Zn-SOD mutant G93A mouse, an animal model of ALS AWARDS, SCHOLARSHIPS, & DISTINCTIONS August 2009 Doctoral Student Award in Nutrition Education and Communication. Presented by the Danone Institute of Canada. May 2009 Ontario Graduate Scholarship (OGS). Declined April 2009 First Place Prize Cell and Molecular Physiology (CAMPS) Section Robert Gunn Student Award Experimental Biology 2009, New Orleans, LA January 2009 Graduate Student Award Competition Finalist. Ontario Exercise Physiology (OEP) 2009, Barrie, ON April 2008 Nutrient-Gene Interaction (NGIRIS) Poster Competition Participant. The American Society for Nutrition (ASN) Experimental Biology 2007, San Diego, CA April 2007 Caroline tum Suden/Frances A. Hellebrandt Professional Opportunity Award. The American Physiological Society (APS) Experimental Biology 2008, Washington, DC Apr 2006 Honourable Mention Biology Undergraduate Symposium McMaster University Sept 2002 McMaster Honour Award. Presented at the Undergraduate Academic Awards Ceremony. Awarded by McMaster University June 2002 Zonta Club of Sault Ste. Marie Award Ontario Scholar EMPLOYMENT EXPERIENCE Nov 2008 – Dec 2008 Administrative Assistant: Specialty Casualty Liberty International Underwriters, Brookfield Place, Toronto, ON Supervisor: Mr. Garth Pepper Sept 2008 – Nov 2008 Laboratory Assistant & Grant Writer School of Kinesiology and Health Science, York University, Toronto, ON Supervisor: Dr. Mazen J. Hamadeh Jan 2008 – Apr 2008 Teaching Assistant: Exercise Physiology KINE 4010 (Jan 2008) School of Kinesiology and Health Science, York University, Toronto, ON Course Coordinator: Dr. David A. Hood Sept 2007 – Dec 2007 Teaching Assistant: Skilled Performance and Motor Learning KINE 3020 School of Kinesiology and Health Science, York University, Toronto, ON Course Coordinator: Dr. Denise Henriques & Professor Merv Mosher Sept 2007 – Dec 2007 Private Statistics Tutor: Univariate Analysis and Design KINE 6010 School of Kinesiology and Health Science, York University, Toronto, ON Apr 2007 – Apr 2008 Laboratory, Research & Technical Assistant School of Kinesiology and Health Science, York University, Toronto, ON Supervisor: Dr. Mazen J. Hamadeh Jan 2007 – Apr 2007 Teaching Assistant: Analysis of Data in Kinesiology I KINE 2050 School of Kinesiology and Health Science, York University, Toronto, ON Course Coordinator: Dr. Hala Tamim & Dr. Chris Ardern Sept 2006 – Dec 2006 Teaching Assistant: Human Physiology II KINE 3012 School of Kinesiology and Health Science, York University, Toronto, ON Course Coordinator: Dr. Michael Connor May 2006 – Aug 2006 Laboratory, Research & Animal Facility Assistant Dept. of Pediatrics, McMaster University Medical Centre, Hamilton, ON Supervisor: Dr. Mark A. Tarnopolsky COMMITTEE MEMBERSHIPS Jan 2009 – Present Graduate Student Member of HISTORY (High Impact Strategies Towards Overweight Reduction in Youth) CIHR Childhood Obesity Research Team Hospital for Sick Children, Toronto, ON Sept 2007 – Sept 2008 Graduate Student Assembly (GSA) Councillor York University, Toronto, ON Sept 2005 – Apr 2006 Executive Board member McMaster Students’ Union (MSU), McMaster University, Hamilton, ON Apr 2004 – Apr 2006 Student Representative Assembly (SRA) member Faculty of Science, McMaster University, Hamilton, ON Apr 2004 – Apr 2006 Ontario Undergraduate Student Alliance (OUSA) delegate representing the MSU McMaster University, Hamilton, ON PROFESSIONAL MEMBERSHIPS
2007 American Physiological Society (APS) 2007 American Society for Nutrition (ASN) 2007 Canadian Obesity Network TECHNICAL SKILLS
and manuscript preparation ANIMAL RESEARCH SKILLS: animal handling, injections and endpoint, exercise training of mice, pre-clinical measurements (measuring body weight, food intake etc.), perfusion of whole animal for immunohistochemistry, insertion of osmotic pumps in rats, surgical removal of muscle and tissue from mice, tail cutting and lysing. LABORATORY RESEARCH SKILLS: lab start-up (ordering and assembling equipment), spectrophotometric enzyme assays, lipid peroxidation assay, protein carbonyl assay, protein quantification and analysis, western blotting and RT-PCR CLINICAL RESEARCH SKILLS: research ethics preparations, patient recruitment (informed consent), bioelectrical impedance analysis (BIA) measurements, skinfold measurements, food intake measurements and administration of visual analogue scales (VAS) VOLUNTEERING June 2007 WALK for ALS participant, ALS Society of Ontario, Ontario Place, Toronto, ON Sept 2006 – Present Research volunteer, Ontario Association of Food Banks (OAFB) volunteer, Toronto, ON Sept 2002 – Apr 2006 Executive member, McMaster Wish Foundation, McMaster University, Hamilton, ON EXTRACURRICULAR ACTIVITIES Jogging & tennis Strong interest in nutrition and health promotion An avid reader and participant in a monthly book club Travelling (recent trips include Mexico, South Korea, China, India and the United Kingdom) Strong supporter and advocate of Amnesty International and the World Society of the Protection of Animals (WSPA). JOURNAL PUBLICATIONS Patel BP, Hamadeh MJ. Nutritional and exercise-based interventions in the treatment of Amyotrophic lateral sclerosis (ALS). Clin Nutr 2009 (accepted on June 2, 2009; ms # YCLNU-D-08-00432R2) . Tables 1-7. Seevaratnam R, Patel BP, Hamadeh MJ. Comparison of total protein concentration in skeletal muscle as measured by the Bradford and Lowry assays. J Biochem 2009;145:791–7. Abstract ABSTRACTS
Patel BP, Tarnopolsky MA, Hamadeh MJ. Caloric restriction increases skeletal muscle apoptosis in the G93A mouse due to impairment in cell stress response and an incomplete compensatory upregulation of antioxidant enzymes. Proceedings of the Ontario Exercise Physiology Conference (2009) (abst.) Patel B, Raha S, Tarnopolsky MA, Hamadeh MJ. Oxidative damage, antioxidant enzymes and mitochondrial energetics following caloric restriction in an animal model of heightened oxidative stress. Proceedings of the 1St Canadian Obesity Student Meeting 2008:23 (abst.). Patel BP, Raha S, Tarnopolsky MA, Hamadeh MJ. Long-term caloric restriction up-regulates antioxidant protein content in female, but exacerbates disease outcomes in male, G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). Proceedings of the CSCN-CSNS Annual Scientific Meeting 2008:SUP13 (abst.). Seevaratnam R, Patel B, Hamadeh MJ. The Bradford assay proves superior to the Lowry assay in determining protein concentration for comparison of nutrient protein interactions in skeletal muscle. Proceedings of the CSCN-CSNS Annual Scientific Meeting 2008:SUP14 (abst.). Patel BP, Raha S, Tarnopolsky MA, Hamadeh MJ. Long-term caloric restriction causes dysregulation in cellular redox status in the skeletal muscle of the Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. FASEB J 2008;22:155.7 (abst.). Abstract Seevaratnam R, Patel B, Hamadeh MJ. Determination of protein concentration in skeletal muscle using two spectrophotometric assays: the Lowry and the Bradford. FASEB J 2008;22:LB252 (abst.). Abstract Patel BP, Raha S, Tarnopolsky MA, Hamadeh MJ. Long-term caloric restriction increases lipid peroxidation and up-regulates Cu/Zn-SOD and UCP3 protein content in the skeletal muscle of the female Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. Proceedings of the Ontario Exercise Physiology Conference 2008:27 (abst.). Seevaratnam R, Patel BP, Hamadeh MJ. To Lowry or to Bradford: validation of 2 spectrophotometric methods for the determination of protein concentration in skeletal muscle. Proceedings of the Ontario Exercise Physiology Conference 2008:26 (abst.). Patel BP, Safdar A, Raha S, Tarnopolsky MA, Hamadeh MJ. Long-term caloric restriction increases lipid peroxidation, but decreases protein oxidation, in the skeletal muscle of the Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. FASEB J 2007;21(6):A818 (abst.). Abstract Patel BP, Hamadeh MJ, Raha S, Tarnopolsky MA. Long-term caloric restriction increases malondialdehyde in the red and white gastrocnemius muscle in the Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. 19th Annu Ontario Biol Day Abstract Book 2006:27 (abst.). http://www.uwo.ca/biology/ontariobiologyday/AbstractBook.pdf Abstract INVITED TALKS February 2006 ART: Residence Life Conference, Trent University, “Unmasking Identity: Discovering the Colours of Your Life” CONFERENCE PRESENTATIONS
Patel BP, Tarnopolsky MA, Hamadeh MJ. Caloric restriction increases skeletal muscle apoptosis in the G93A mouse due to impairment in cell stress response and an incomplete compensatory upregulation of antioxidant enzymes. Ontario Exercise Physiology Conference, Barrie, ON, January 23-25, 2009 (podium presentation). Patel B, Raha S, Tarnopolsky MA, Hamadeh MJ. Oxidative damage, antioxidant enzymes and mitochondrial energetics following caloric restriction in an animal model of heightened oxidative stress. 1St Canadian Obesity Student Meeting, Laval, QUE, June 4-6, 2008 (podium presentation). http://obesity.ulaval.ca/upload/documents/PresentationSchedule.pdf Patel BP, Raha S, Tarnopolsky MA, Hamadeh MJ. Long-Term Caloric Restriction Up-Regulates Antioxidant Protein Content in Female, But Exacerbates Disease Outcomes in Male, G93A Mice. 7th Annual Scientific meeting of the Canadian Society of Clinical Nutrition – Canadian Society for Nutritional Sciences Toronto, ON, May 29 - 31, 2008 (poster presentation). Patel B, Raha S, Tarnopolsky MA, Hamadeh MJ. Long-term caloric restriction causes dysregulation in cellular redox status in the skeletal muscle of the Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. Experimental Biology ‘08, San Diego, CA, April 5-9, 2008 (podium presentation). Patel B, Raha S, Tarnopolsky MA, Hamadeh MJ. Long-term caloric restriction increases lipid peroxidation and up-regulates Cu/Zn-SOD and UCP3 protein content in the skeletal muscle of the female Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. Ontario Exercise Physiology Conference, Barrie, ON, January 25-27, 2008 (podium presentation). Patel BP, Safdar A, Raha S, Tarnopolsky MA, Hamadeh MJ. Long-term caloric restriction increases lipid peroxidation, but decreases protein oxidation, in the skeletal muscle of the Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. EB 2007, Washington DC, April 28-May 2, 2007 (poster presentation). Patel BP, Hamadeh MJ, Raha S, Tarnopolsky MA. Long-term caloric restriction increases malondialdehyde in the red and white gastrocnemius muscle in the Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. 19th Annu Ontario Biol Day, London, ON, March 18-19, 2006 (podium presentation). MANUSCRIPTS IN PREPARATION Patel BP, Safdar A, Raha S, Tarnopolsky MA, Hamadeh MJ. Long-term caloric restriction hastens clinical onset, disease progression and endpoint in the Cu/Zn-SOD mutant G93A mouse, an animal model of Amyotrophic lateral sclerosis (ALS).
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Last updated: January 30, 2009 |