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Mazen J. Hamadeh : Curriculum Vitae |
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ACADEMIC POSITIONS Associate Professor, School of Kinesiology and Health Science, York University (2010-present) EDUCATION Postdoctoral Fellow Ph.D., Human Nutrition (Dean’s Honour List) M.Sc., Nutritional Sciences JOURNAL PUBLICATIONS Moreira TS, Hamadeh MJ. The role of vitamin D deficiency and low calcium/dairy intake in the pathogenesis of type 2 diabetes mellitus. e-SPEN Eur e-J Clin Nutr Metab 2010;5:e1-e11. Abstract doi: 10.1016/j.eclnm.2010.05.001 Safdar A, Hamadeh MJ, Kaczor JJ, Raha S, deBeer J, Tarnopolsky MA. Sedentary mitochondrial aging syndrome in humans: dysfunctional Nrf2/Keap1 redox signaling and aberrant mitochondrial homeostasis in the skeletal muscle of frail old. PLoS ONE 2010;5:e10778. Abstract Patel BP, Safdar A, Raha S, Tarnopolsky MA, Hamadeh MJ. Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of amyotrophic lateral sclerosis. PLoS One 2010;5:e9386. Abstract
Crane JD, Devries MC, Safdar A, Hamadeh MJ, Tarnopolsky MA. The Effect of aging on human skeletal muscle mitochondrial and IMCL ultrastructure. J Gerontol A Biol Sci Med Sci 2010;65:119-28. Abstract Fu M-H, Maher A, Hamadeh MJ, Ye C, Tarnopolsky MA. Exercise, sex, menstrual cycle phase and 17β-estradiol influence metabolism related genes in human skeletal muscle. Physiol Genomics 2009;40:34-47. Abstract Patel BP, Hamadeh MJ. Nutritional and exercise-based interventions in the treatment of amyotrophic lateral sclerosis.
Clin Nutr 2009;28:604-17.
Abstract Tables 1-7 Seevaratnam R, Patel BP, Hamadeh MJ. Comparison of total protein concentration in skeletal muscle as measured by the Bradford and the Lowry assays. J Biochem 2009;145:791–7. Abstract Timmons BW, Hamadeh MJ, Tarnopolsky MA. A comparison of two methods for the determination of plasma IL-6 in humans at rest and following exercise. Eur J Appl Physiol 2009;105:13-8. Abstract Devries MC, Samjoo IA, Hamadeh MJ, Tarnopolsky MA. Effect of twelve weeks of endurance training on hepatic lipid content and liver enzymes in lean and obese men and women. Obesity 2008;16:2281-8. Abstract Devries MC, Hamadeh MJ, Glover AW, Raha S, Samjoo IA, Tarnopolsky MA. Endurance training without weight loss lowers systemic, but not muscle, oxidative stress with no effect on inflammation in lean and obese women. Free Radic Biol Med 2008;45:503-11. Abstract Lord HL, Rosenfeld J, Raha S, Hamadeh MJ. Automated derivatization and analysis of malondialdehyde using column switching sample preparation HPLC with fluorescence detection. J Sep Sci 2008;31:387-40. Abstract Devries MC, Lowther SA, Glover AW, Hamadeh MJ, Tarnopolsky MA. IMCL area density, but not IMCL utilization, are higher in women during moderate intensity endurance exercise as compared with men. Am J Physiol Regul Integr Comp Physiol 2007;293:R2336-42. Abstract Tarnopolsky MA, Rennie CD, Robertshaw HA, Fedak-Tarnopolsky SN, Brose AN, Devries MC, Hamadeh MJ. The influence of endurance exercise training and sex on intramyocellular lipid and mitochondrial ultrastructure. Am J Physiol Regul Integr Comp Physiol 2007;292:R1271-8. Abstract Hamadeh MJ, Tarnopolsky MA. Transient caloric restriction in early adulthood hastens disease endpoint in male, but not female, Cu/Zn-SOD mutant G93A mice. Muscle Nerve 2006;34:709-19. Abstract Devries MC, Hamadeh MJ, Phillips SM, Tarnopolsky MA. Menstrual cycle phase and sex influence muscle glycogen utilization and glucose Ra, Rd, and MCR during moderate intensity endurance exercise. Am J Physiol Regul Integr Comp Physiol 2006;291:1120-8. Abstact Timmons BW, Hamadeh MJ, Tarnopolsky MA. No effect of short-term 17-b-estradiol supplementation in healthy men on systemic inflammatory responses to exercise. Am J Physiol Regul Integr Comp Physiol 2006;291:R285-90. Abstract Devries MC, Hamadeh MJ, Graham TE, Tarnopolsky MA. 17-β-estradiol supplementation decreases glucose Ra and Rd with no effect on glycogen utilization during moderate intensity exercise in men. J Clin Endocrinol Metab 2005;90:6218-25. Abstract Hoffer LJ, Hamadeh MJ, Robitaille L, Norwich KH. Human sulfate kinetics. Am J Physiol Regul Integr Comp Physiol 2005;289:R1372-80. Abstract Timmons BW, Hamadeh MJ, Devries MC, Tarnopolsky MA. Influence of gender, menstrual phase and oral contraceptive use on immunological changes in response to prolonged cycling. J Appl Physiol 2005;99:979-85. Abstract Hamadeh MJ, Devries MC, Tarnopolsky MA. Estrogen supplementation reduces whole body leucine and carbohydrate oxidation and increases lipid oxidation in men during endurance exercise. J Clin Endocrinol Metab 2005;90:3592-9. Abstract Hamadeh MJ, Rodriguez MC, Kaczor JJ, Tarnopolsky MA. Caloric restriction transiently improves motor performance but hastens clinical onset in the Cu/Zn-SOD mutant G93A mouse. Muscle Nerve 2005;31:214-20. Abstract Hamadeh MJ, Hoffer LJ. Effect of protein restriction on sulfur amino acid catabolism in insulin-dependent diabetes mellitus. Am J Physiol Endocrinol Metab 2003;284:E382-9. Abstract Hamadeh MJ, Schiffrin A, Hoffer LJ. Sulfate production depicts fed-state adaptation to protein restriction in humans. Am J Physiol Endocrinol Metab 2001;281:E341-8. Abstract Hamadeh MJ, Hoffer LJ. Effect of protein restriction on 15N transfer from dietary [15N]alanine and [15N]Spirulina platensis into urea. Am J Physiol Endocrinol Metab 2001;281:E349-56. Abstract Hamadeh MJ, Hoffer LJ. Use of sulfate production as a measure of short-term sulfur amino acid catabolism in humans. Am J Physiol Endocrinol Metab 2001;280:E857-66. Abstract Hoffer LJ, Kaplan LN, Hamadeh MJ, Grigoriu AC, Baron M. Sulfate could mediate the effects of glucosamine sulfate therapy. Metabolism 2001;50:767-70. Abstract Hamadeh MJ, Robitaille L, Boismenu D, Hongsprabhas P, Mamer OA, Hoffer LJ. Extracellular water volume measured with the stable isotope Na234SO4. J Nutr 1999;129:722-9. Abstract Hamadeh MJ, Hoffer LJ. Tracer methodology underestimates changes in plasma urea appearance in humans. Am J Physiol 1998;274:E547-53. Abstract Hoffer LJ, Taveroff A, Hamadeh MJ. Dietary protein restriction alters glucose but not protein metabolism in non-insulin-dependent Diabetes Mellitus. Metabolism 1998;47 (9):1145-51. Abstract Boismenu D, Robitaille L, Hamadeh MJ, Hongsprabhas P, Hoffer LJ, Mamer OA. Measurement of sulfate concentrations and tracer/tracee ratios in biological fluids by electrospray tandem mass spectrometry. Anal Biochem 1998;261:93-9. Abstract Hoffer LJ, Taveroff A, Robitaille L, Hamadeh MJ, Mamer O. Effects of leucine on whole-body leucine, valine and threonine metabolism in humans. Am J Physiol 1997;272:E1037-42. Abstract Cunnane SC, Hamadeh MJ, Liede AC, Thompson LU, Wolever TMS, Jenkins DJ. Nutritional attributes of traditional flaxseed in healthy young adults. Am J Clin Nutr 1995;61:62-8. Abstract Cunnane SC, Ganguli S, Menard C, Liede AC, Hamadeh MJ, Chen Z-Y, Wolever TMS, Jenkins DJA. High alpha-linolenic acid flaxseed (Linum usitatissimum): some nutritional properties in humans. Br J Nutr 1993;69:443-53. Abstract Cunnane SC, Chen Z-Y, Yang J, Liede AC, Hamadeh M, Crawford MA. Alpha-linolenic acid in humans: direct functional role or dietary precursor. Nutrition 1991;7 (6):437-9. BOOKS Hamadeh MJ, Adgoke OAJ. Enhancing the Understanding of Human Nutrition: A student guide to Understanding Nutrition. Nelson Education Ltd, Toronto, ON, 2009, pp.176. (ISBN 0176478078). PROCEEDINGS Hamadeh MJ, Liede AC, Ganguli S, Wolever TMS, Cunnane SC. Nutritional aspects of flaxseed in the human diet. Proceedings of the 54th Annual Meeting of the Flax Institute of the United States 1992:48-53. Liede AC, Hamadeh M, Wolever TMS, Cunnane SC. Safety aspects of flaxseed in the human diet. Proceedings of the 54th Annual Meeting of the Flax Institute of the United States 1992:54-58. ABSTRACTS Samjoo IA, Safdar A, Hamadeh MJ, Glover AW, Mocellin NJ, Santana J, Steinberg GR, Raha S, Gallagher I, Timmons JA, Tarnopolsky MA. Endurance training augments skeletal muscle mitochondrial function and improves insulin resistance by modulating inflammation in obese men. Proceedings of the 2nd Canadian Obesity Student Meeting 2010:24 (abst.). Abstract Solomon JA, Hamadeh MJ. Neuromuscular disease and ethics: considerations of endpoint in a mouse model of Lou Gehrig’s disease. Muscle Health Awareness Day 2010:34 (abst.). Gianforcaro A, Hamadeh MJ. Is adequate really enough? Vitamin D3 supplementation at 10x the AI blunts disease severity and enhances functional outcomes in an animal model of Lou Gehrig’s disease. A pilot study. Muscle Health Awareness Day 2010:19 (abst.). Solomon JA, Hamadeh MJ. Does vitamin D and calcium supplementation have an effect on markers of type 2 diabetes? – A proposed clinical trial. Bodies of Knowledge Graduate Research Conference 2010:14 (abst.). Abstract Gianforcaro A, Hamadeh MJ. D throws Lou Gehrig’s a curveball: D3 attenuates disease severity and functional decline. Bodies of Knowledge Graduate Research Conference 2010:15 (abst.). Abstract Solomon JA, Hamadeh MJ. Does D Deliver in Diabetics? A Proposed double blind randomized control trial. Proceedings of the 2010 YIHR Graduate Student Symposium http://www.yorku.ca/yihr/Students/StudentSymposium/index.html (abst.). Abstract Samjoo IA, Safdar A, Hamadeh MJ, Raha S, Kujoth GC, Prolla TA, Tarnopolsky MA. Mitochondrial dysfunction is not a causative factor in the pathogenesis of obesity. FASEB J. 2010 24:1045.9 (abst.). Abstract Samjoo IA, Safdar A, Hamadeh MJ, Akhtar M, Raha S, Timmons JA, Tarnopolsky MA. Endurance training-mediated differential regulation of miRNAs in skeletal muscle of lean and obese men. FASEB J. 2010 24:806.14 (abst.). Abstract Gianforcaro A, Hamadeh MJ. Dietary vitamin D3 at 10 fold the adequate intake may attenuate disease severity in the transgenic G93A mouse model of ALS. FASEB J 2010 24:lb396 (abst.). Abstract Gianforcaro A, Hamadeh MJ. The effect of vitamin D on the G93A Mouse model of ALS. Proceedings of the Ontario Exercise Physiology Conference 2010:32 (abst.). Abstract
Solomon JA, Hamadeh MJ. The role of vitamin D and calcium supplementation in modulating the pathogenesis of type 2 diabetes mellitus. Proceedings of the Ontario Exercise Physiology Conference 2010:58 (abst.). Abstract Hamadeh MJ, Seevaratnam R. Coffee and caffeine decrease markers of oxidative stress in G93A mice: coffee improves antioxidant enzyme capacity in males. Ann Nutr Metab 2009;55(Suppl.1):190 (abst.). Abstract
Ma X, Hamadeh MJ, Foster J, Tarnopolsky MA. Brain derived neurotrophic factor promotes cell survival and neuronal differentiation in the dentate gyrus of G93A mice.
Appl Physiol Nutr Metab 2009;34:1142 (abst.).
Abstract Samjoo IA, Hamadeh MJ, Santana J, Raha S, Tarnopolsky MA. Obesity does not impair mitochondrial adaptations to endurance exercise.
Appl Physiol Nutr Metab 2009;34:1154 (abst.).
Abstract Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Coffee, caffeine, and chlorogenic acid reduce oxidative stress and apoptosis, and improve antioxidant enzyme capacity in male G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). Proceedings of the CSCN-CSNS Annual Scientific Meeting 2009:138 (abst.). Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Caffeine increases apoptosis and decreases antioxidant enzyme capacity, in spite of decreasing markers of oxidative stress in female G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). Proceedings of the CSCN-CSNS Annual Scientific Meeting 2009:276 (abst.). Patel BP, Tarnopolsky MA, Hamadeh MJ. Long-term caloric restriction increases apoptosis and decreases cell stress response, despite an elevation in antioxidant enzyme capacity in the skeletal muscle of the Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. FASEB J 2009;23:109.1 (abst.). Abstract Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Caffeine reduces motor performance and antioxidant enzyme capacity in the brain of female G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). FASEB J 2009;23:963.3 (abst.). Abstract Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Coffee increases antioxidant enzyme capacity in the brain of male G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). FASEB J 2009;23:109.6 (abst.). Abstract Patel BP, Tarnopolsky MA, Hamadeh MJ. Caloric restriction increases skeletal muscle apoptosis in the G93A mouse due to impairment in cell stress response and an incomplete compensatory upregulation of antioxidant enzymes. Proceedings of the Ontario Exercise Physiology Conference 2009:27 (abst.). Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Coffee improves antioxidant capacity in male G93A mice, whereas caffeine reduces it in female G93A mice, an animal model of Amyotrophic lateral sclerosis (ALS). Proceedings of the Ontario Exercise Physiology Conference 2009:27 (abst.). Samjoo IA, Hamadeh MJ, Tarnopolsky MA. Endurance training, independent of weight loss, improves mitochondrial oxidative capacity and enhances insulin signal transduction in lean and obese men. Proceedings of the 2008 APS Intersociety Meeting: The Integrative Biology of Exercise V 2008:64 (abst.). Samjoo IA, Hamadeh MJ, Glover AW, Mocellin NJ, Tarnopolsky MA. Endurance training redistributes intramyocellular lipids from the subsarcolemmal to the intramyofibrillar region in skeletal muscle of lean and obese men. Proceedings of the 2008 APS Intersociety Meeting: The Integrative Biology of Exercise V 2008:72 (abst.). Patel BP, Raha S, Tarnopolsky MA, Hamadeh MJ. Oxidative damage, antioxidant enzymes and mitochondrial energetics following caloric restriction in an animal model of heightened oxidative stress. Proceedings of the 1st Canadian Obesity Student Meeting 2008:22. Hamadeh MJ, Tarnopolsky MA. Chlorogenic acid, a coffee polyphenol and antioxidant, hastens clinical onset of disease but prolongs life span in the G93A mouse, an animal model of ALS, as compared with caffeine. FASEB J 2008;22:702.11 (abst.). Abstract Hamadeh MJ, Tarnopolsky MA. Estrogen supplementation in men increases serum C-reactive protein concentration before, during and after moderate intensity endurance exercise. FASEB J 2007;21(5):A579 (abst.). Abstract Hamadeh MJ, Devries MC, Raphael DJ, Safdar A, Tarnopolsky MA. Gender-based differential infiltration of CRP from the blood into skeletal muscle. FASEB J 2007;21(6):A935 (abst.). Abstract Patel BP, Safdar A, Raha S, Tarnopolsky MA, Hamadeh MJ. Long-term caloric restriction increases lipid peroxidation, but decreases protein oxidation, in the skeletal muscle of the Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. FASEB J 2007;21(6):A818 (abst.). Abstract Devries MC, Hamadeh MJ, Glover S, McCready C, Raha S, Tarnopolsky MA. Antioxidant enzyme protein content in lean and obese women prior to and following a 12-week endurance training protocol. FASEB J 2007;21(5):A668 (abst.). Abstract Raphael DJ, Hamadeh MJ, Tarnopolsky MA. Antioxidant supplementation attenuates the exercise-induced increase in plasma CK, but not CRP, during moderate intensity endurance exercise in men. FASEB J 2007;21(6):A932 (abst.). Abstract Safdar A, Kaczor JJ, Hamadeh MJ, Raha S, Tarnopolsky MA. Mitochondrial dysfunction is associated with increased oxidative stress and inflammation, and Nrf2-mediated antioxidant dysregulation with frail aging. FASEB J 2007;21(6):A937 (abst.). Abstract D’Sa H, Hettinga B, Safdar A, Tarnopolsky MA, Hamadeh MJ, Raha S. The use of DNPH-derivatized protein carbonyls as a marker of oxidative stress in mouse heart and liver. FASEB J 2007;21:LB478 (abst.). Abstract Raphael DJ, Hamadeh MJ, Kaczor JJ, Baker SK, Tarnopolsky MA. Antioxidant supplementation in men attenuates the exercise-induced increase in mRNA expression of PDK4 and IRF-1 following prolonged cycling. Med Sci Sports Exerc 2006;38(11):S30 (abst.). Hamadeh MJ, Tarnopolsky MA. The use of oral contraceptives in women alters the differences in substrate oxidation between phases of the menstrual cycle. FASEB J 2006;20(5):A1468 (abst.). Abstract Fu M-H, Hamadeh MJ, Tarnopolsky MA. Women have higher skeletal muscle mRNA content of BCKDK compared with men. FASEB J 2006;20(5):A1434 (abst.). Abstract Fu M-H, Hamadeh MJ, Ye C, Tarnopolsky MA. Menstrual phase, sex, estradiol supplementation in men and exercise influence the mRNA content of genes involved in carbohydrate metabolism. FASEB J 2006;20(5): A1434 (abst.). Abstract Patel BP, Hamadeh MJ, Raha S, Tarnopolsky MA. Long-term caloric restriction increases malondialdehyde in the red and white gastrocnemius muscle in the Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. 19th Annu Ontario Biol Day Abstract Book 2006:27 (abst.). http://www.uwo.ca/biology/ontariobiologyday/AbstractBook.pdf Abstract Hamadeh MJ, Tarnopolsky MA. Estrogen supplementation decreases 24-h whole body protein breakdown in men. Can J Exerc Physiol 2005;30 (suppl.):S34 (abst.). Fu M-H, Hamadeh MJ, Tarnopolsky MA. The female sex, menstrual phase, estradiol supplementation and exercise differently and selectively influence different aspects of lipid metabolism, transport and oxidation. Can J Exerc Physiol 2005;30 (suppl.):S30 (abst.). Hamadeh MJ, Tarnopolsky MA. Long-term caloric restriction hastens clinical onset, disease progression and endpoint in the Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. Ann Nutr Metab 2005;49 (Suppl 1):164 (abst.). Hamadeh MJ, Tarnopolsky MA. Transient caloric restriction hastens disease endpoint in male, but not female, Cu/Zn-SOD mutant G93A mice, an animal model of ALS. Proceedings of the 48th Annual Meeting of the Canadian Federation of Biological Societies 2005:75 (abst.). Fu M-H, Hamadeh MJ, Tarnopolsky MA. The female sex, but not menstrual cycle or acute estradiol supplementation, is associated with higher skeletal muscle mRNA content of SREBP-1, GPAT and FATm before and after moderate intensity endurance exercise. Proceedings of the 48th Annual Meeting of the Canadian Federation of Biological Societies 2005:123 (abst.). Devries MC, Hamadeh MJ, Tarnopolsky MA. Estrogen supplementation decreases glucose Ra and Rd during moderate intensity endurance exercise in men. Proceedings of the 48th Annual Meeting of the Canadian Federation of Biological Societies 2005:121 (abst.). Devries MC, Hamadeh MJ, Phillips SM, Tarnopolsky MA. Menstrual cycle phase and gender influence glucose Ra, Rd and MCR during moderate intensity endurance exercise. Proceedings of the 48th Annual Meeting of the Canadian Federation of Biological Societies 2005:92 (abst.). Devries MC, Hamadeh MJ, Tarnopolsky MA. Effects of 17-β-estradiol supplementation on carbohydrate metabolism during exercise in men. Proceedings of the Ontario Exercise Physiology Conference 2005 (abst.). Hamadeh MJ, Devries MC, Tarnopolsky MA. The effect of menstrual phase on leucine oxidation at rest and during moderate intensity exercise. Physiologist 2004;47:306-7 (abst.). Fu M-H, Hamadeh MJ, Tarnopolsky MA. Gender, exercise and menstrual phase selectively and independently influence mRNA expression of genes involved in fat metabolism in human skeletal muscle. The Physiologist 2004;47:341 (abst.). Devries MC, Hamadeh MJ, Tarnopolsky MA. Menstrual cycle phase and gender influence muscle proglycogen and total glycogen storage and utilization during exercise. The Physiologist 2004;47:300 (abst.). Hamadeh MJ, Devries MC, Tarnopolsky MA. Estrogen supplementation reduces leucine oxidation at rest and during moderate intensity endurance exercise in men. Med Sci Sports Exerc 2004;36(5):S194 (abst.). Abstract Devries MC, Hamadeh MJ, Tarnopolsky MA. Estrogen supplementation decreases muscle proglycogen and total glycogen at rest and following exercise in men. Med Sci Sports Exerc 2004;36(5):S176-7 (abst.). Abstract Tarnopolsky MA, Timmons BW, Hamadeh MJ, Devries MC, Phillips LL. Inflammatory-related cytokine response to endurance exercise in healthy men following estrogen supplementation. Med Sci Sports Exerc 2004;36(5):S131 (abst.). Abstract Hamadeh MJ, Rodriguez MC, Kaczor JJ, Tarnopolsky MA. Caloric restriction improves motor performance but hastens clinical onset in G93A transgenic mice, a model of amyotrophic lateral sclerosis. Late Breaking Abstracts for Experimental Biology ’04, Washington D.C. 2004:A72 (abst.). Devries MC, Hamadeh MJ, Graham TE, Tarnopolsky MA. Estrogen supplementation decreases muscle proglycogen and total glycogen in men at rest and following exercise in men. Proceedings of the Ontario Exercise Physiology Conference 2004 (abst.). Hamadeh MJ, Robitaille L, Norwich KH, Hoffer LJ. Whole-body sulfation rate of normal humans. FASEB J 2004;18(5):A912 (abst.). Hamadeh MJ, Devries MC, Timmons BW, Tarnopolsky MA. Estrogen increases the oxidation of fatty acids as a fuel source during 90 min of moderate intensity endurance exercise. Proceedings of the 46th Annual Meeting of the Canadian Federation of Biological Societies 2003:75 (abst.). Timmons BW, Hamadeh MJ, Devries MC, Phillips LL, Tarnopolsky MA. Effects of menstrual phase in women and estrogen supplementation in men on immune responses to endurance exercise. Proceedings of the 46th Annual Meeting of the Canadian Federation of Biological Societies 2003:86 (abst.). Hamadeh MJ, Taveroff A, Hoffer LJ. Whole-body sulfur amino acids are preferentially retained in the first 24 hours following dietary protein restriction in healthy and insulin-dependent diabetic humans. Proceedings of the 45th Annual Meeting of the Canadian Federation of Biological Societies 2002:81 (abst.). Hamadeh MJ, Hoffer LJ. Fed-state sulfate production following a high protein test meal in normal and diabetic humans. FASEB J 2002;16(4):A257 (abst.). Hamadeh MJ, Schiffrin A, Hoffer LJ. Metabolic N and S balances in insulin-dependent diabetes. Proceedings of the 43rd Annual Meeting of the Canadian Federation of Biological Societies 2000:97 (abst.). Hamadeh MJ, Hoffer LJ. Nontracer (but not tracer) methods accurately depict sulfate production in humans. FASEB J 2000;14(4):A795 (abst.). Hamadeh MJ, Hoffer LJ. Infused essential amino acids redirect sulfur amino acids from a non-protein to a protein bound form. FASEB J 2000;14(4):A765 (abst.). Hamadeh MJ, Hoffer LJ. Transfer of 15N in 15N-alanine (15N-ALA) and in 15N-Spirulina platensis (15N-SPI) from a meal into urea provides comparable measures of the increased dietary protein conservation associated with protein restriction. FASEB J 1999;13(4):A52 (abst.). Hamadeh MJ, Hoffer LJ. Urinary sulfate excretion is an indicator of whole-body amino acid oxidation. FASEB J 1999;13(4):A566 (abst.). Hamadeh MJ, Boismenu D, Robitaille L, Hongsprabhas P, Mamer OA, Hoffer LJ. Human extracellular fluid volume measured using the stable isotope 34S-Na2SO4. Clin Invest Med 1998;21 (suppl.):S35 (abst.). Hamadeh MJ, Hoffer LJ, Taveroff A, Robitaille L, Mamer OA. Effect of intravenous leucine on whole-body proteolysis as assessed using leucine, valine and threonine tracers. FASEB J 1997;11(3):A438 (abst.). Hoffer LJ, Taveroff A, Hamadeh MJ. Protein restriction affects glucose but not protein metabolism in NIDDM. Am J Clin Nutr 1997;66:220 (abst.). Hamadeh MJ, Hoffer LJ. Tracer methodology underestimates changes in plasma urea rate of appearance (Ra). FASEB J 1996;10(3):A472 (abst.). Hamadeh M, Derkach P, Wolever TMS, Cunnane SC. The effect of dietary flaxseed on n-3 fatty acids, cholesterol profiles and laxation in the institutionalized elderly. INFORM 1992;3:517 (abst.). Cunnane SC, Ganguli S, Chen Z-Y, Hamadeh M, Liede A, Wolever T, Jenkins D, Vuksan V. Application of flax in evaluating and controlling hyperlipidemia. INFORM 1991;2:574 (abst.). Cunnane SC, Ganguli S, Menard C, Liede A, Hamadeh M. Potential uses of flax in human nutrition. INFORM 1991;2:574 (abst.). INVITED TALKS June 2, 2009 - The 2009 CSCN-CSNS Annual Conference, Quebec City, QC, “Dietary manipulations in the G93A mouse, an animal model of ALS”. July 19, 2008 - Diabetes, Exercise and Sports Association 2008 International Conference, Toronto, ON, “Nutrition, Hydration and Supplements” March 10, 2006 - Kinesiology and Health Science, York University, “The influence of 17-β-estradiol, menstrual phase and gender on substrate oxidation and protein metabolism during moderate intensity endurance exercise” and “Caloric restriction in the G93A mouse, an animal model of ALS” November 23, 2005 - Pediatrics Grand Rounds, McMaster University, “Caloric restriction in the G93A mouse, an animal model of ALS/SMA” November 22, 2004 - Human Biology and Nutritional Sciences, University of Guelph, “Gender differences in substrate oxidation and protein metabolism during moderate intensity endurance exercise” September 17, 2004 - Pharmanex, Provo, UT, “Adaptation to protein restriction in healthy people and diabetic patients” August 12, 2004 - Human Nutrition and Foods, West Virginia University, “Whole body protein metabolism” February 25, 2003 - Entelos, Foster City, CA, “Methods for detecting abnormal adaptation to protein restriction with special reference to insulin-dependent diabetes mellitus” February 25, 2002 - Health Sciences, Boston University, “Methods for detecting abnormal adaptation to protein restriction with special reference to insulin-dependent diabetes mellitus” February 15, 2002 - College of Pharmacy and Nutrition, University of Saskatchewan, “Methods for detecting abnormal adaptation to protein restriction with special reference to insulin-dependent diabetes mellitus” August 24, 2001 - Foods and Nutrition, Purdue University, “Methods for detecting abnormal adaptation to protein restriction with special reference to insulin-dependent diabetes mellitus” CONFERENCE PRESENTATIONS Hamadeh MJ, Tarnopolsky MA. Chlorogenic acid, a coffee polyphenol and antioxidant, hastens clinical onset of disease but prolongs life span in the G93A mouse, an animal model of ALS, as compared with caffeine. EB 2008, San Diego, April 5-9, 2008. Hamadeh MJ, Devries MC, Raphael DJ, Safdar A, Tarnopolsky MA. Gender-based differential infiltration of CRP from the blood into skeletal muscle. Experimental Biology '07, Washington DC, April 28-May 2, 2007. Hamadeh MJ, Tarnopolsky MA. Estrogen supplementation in men increases serum C-reactive protein concentration before, during and after moderate intensity endurance exercise. Experimental Biology '07, Washington DC, April 28-May 2, 2007. Hamadeh MJ, Tarnopolsky MA. The use of oral contraceptives in women alters the differences in substrate oxidation between phases of the menstrual cycle. Experimental Biology ‘06, San Francisco, April 1-5, 2006. Hamadeh MJ, Tarnopolsky MA. Estrogen supplementation decreases 24-h whole body protein breakdown in men. CSEP 2005, Gatineau, Quebec, November 9-12, 2005. Hamadeh MJ, Tarnopolsky MA. Long-term caloric restriction hastens clinical onset, disease progression and endpoint in the Cu/Zn-SOD mutant G93A mouse, an animal model of ALS. 18th International Congress of Nutrition, Durban, South Africa, September 19-23, 2005. Hamadeh MJ, Tarnopolsky MA. Transient caloric restriction hastens disease endpoint in male, but not female, Cu/Zn-SOD mutant G93A mice, an animal model of ALS. 48th Annual Meeting of the Canadian Federation of Biological Societies, Guelph, June 21-24, 2005. Hamadeh MJ, Devries MC, Tarnopolsky MA. The effect of menstrual phase on leucine oxidation at rest and during moderate intensity exercise. The 2004 APS Intersociety Meeting: The Integrative Biology of Exercise, Austin, Texas, October 6-9, 2004. Hamadeh MJ, Devries MC, Tarnopolsky MA. Estrogen supplementation reduces leucine oxidation at rest and during moderate intensity endurance exercise in men. 51st Annual Meeting of the American College of Sports Medicine, Indianapolis, June 2-5, 2004 (podium presentation). Hamadeh MJ, Robitaille L, Norwich KH, Hoffer LJ. Whole-body sulfation rate of normal humans. Experimental Biology ‘04, Washington D.C., April 17-21, 2004. Hamadeh MJ, Rodriguez MC, Kaczor JJ, Tarnopolsky MA. Caloric restriction improves motor performance but hastens clinical onset in G93A transgenic mice, a model of amyotrophic lateral sclerosis. Experimental Biology ‘04, Washington D.C., April 17-21, 2004. Hamadeh MJ, Devries MC, Timmons BW, Tarnopolsky MA. Estrogen increases the oxidation of fatty acids as a fuel source during 90 min of moderate intensity endurance exercise. 46th Annual Meeting of the Canadian Federation of Biological Societies, Ottawa, June 12-14, 2003. Hamadeh MJ, Taveroff A, Hoffer LJ. Whole-body sulfur amino acids are preferentially retained in the first 24 hours following dietary protein restriction in healthy and insulin-dependent diabetic humans. 45th Annual Meeting of the Canadian Federation of Biological Societies, Montreal, June 12-15, 2002. Hamadeh MJ, Hoffer LJ. Fed-state sulfate production following a high protein test meal in normal and diabetic humans. Experimental Biology 2002, New Orleans, April 20-24, 2002. Hamadeh MJ, Schiffrin A, Hoffer LJ. Metabolic N and S balances in insulin-dependent diabetes. 43rd Annual Meeting of the Canadian Federation of Biological Societies, Ottawa, June 22-25, 2000 (podium presentation). Hamadeh MJ, Hoffer LJ. Nontracer (but not tracer) methods accurately depict sulfate production in humans. Experimental Biology 2000, San Diego, April 15-18, 2000 (podium presentation). Hamadeh MJ, Hoffer LJ. Infused essential amino acids redirect sulfur amino acids from a non-protein to a protein bound form. Experimental Biology 2000, San Diego, April 15-18, 2000. Hamadeh MJ, Boismenu D, Robitaille L, Hongsprabhas P, Mamer OA, Hoffer LJ. The use of the stable isotope 34S-Na2SO4 to measure human extracellular fluid volume. University of Montreal/McGill University 3rd Annual Research Day, Montreal, May 28, 1999. Hamadeh MJ, Hoffer LJ. Transfer of 15N in 15N-alanine (15N-ALA) and in 15N-Spirulina platensis (15N-SPI) from a meal into urea provides comparable measures of the increased dietary protein conservation associated with protein restriction. Experimental Biology ‘99, Washington D.C., April 17-21, 1999 (podium presentation). Hamadeh MJ, Hoffer LJ. Urinary sulfate excretion is an indicator of whole-body amino acid oxidation. Experimental Biology ‘99, Washington D.C., April 17-21, 1999. Hamadeh MJ, Hoffer LJ. Human sulfur metabolism: new approaches. Montreal Stable Isotope Interest Group, Montreal, April 7, 1999 (podium presentation). Hamadeh MJ, Boismenu D, Robitaille L, Hongsprabhas P, Mamer OA, Hoffer LJ. Human extracellular fluid volume measured using the stable isotope 34S-Na2SO4. The Canadian Society for Clinical Investigation Annual Meeting, Toronto, September 24-27, 1998. Hamadeh MJ, Hoffer LJ, Taveroff A, Robitaille L, Mamer OA. Effect of intravenous leucine on whole-body proteolysis as assessed using leucine, valine and threonine tracers. Experimental Biology ‘97, New Orleans, April 6-9, 1997 (podium presentation). Hamadeh MJ, Hoffer LJ. Tracer methodology underestimates changes in plasma urea rate of appearance (Ra). Experimental Biology ‘96, Washington D.C., April 14-17, 1996. Hamadeh M, Derkach P, Wolever TMS, Cunnane SC. The effect of dietary flaxseed on n-3 fatty acids, cholesterol profiles and laxation in the institutionalized elderly. 83rd American Oil Chemists' Society Annual Meeting, Toronto, May 10-14, 1992 (podium presentation). Hamadeh MJ, Liede AC, Ganguli S, Wolever TMS, Cunnane SC. Nutritional aspects of flaxseed in the human diet. 54th Annual Meeting of the Flax Institute of the United States, Fargo, January 30-31, 1992 (podium presentation). |
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Last updated: July 2, 2010
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