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Home | Curriculum Vitae

 

Rajini Seevaratnam, BSc

 

 

EDUCATION

 


Sept 2007 – Present                  Master of Science

School of Kinesiology and Health Science, Faculty of Health

York University, Toronto, ON

 

Thesis: The effects of coffee, caffeine, and chlorogenic acid supplementation on molecular outcome measures of oxidative stress and apoptosis in brain tissue of Cu/Zn SOD1 mutant G93A mice, an animal model of Amyotrophic Lateral Sclerosis (ALS).

 

Sept 2003 – Apr 2007                Honours Bachelor of Science

Specialization in Kinesiology

School of Kinesiology, Faculty of Health Science

University of Western Ontario, London, ON

 

Fourth Year Independent Study: Literary review and seminar presentation of ALS analyzing the potential mechanisms of neurodegeneration, the difficulties in clinical diagnosis, and the psychological impacts on both patients and their caregivers. 

 

 

AWARDS, SCHOLARSHIPS, & DISTINCTIONS

 

April 2009                       Selected for APS Media Release, EB 2009, New Orleans, LA, April 18-22, 2009

· NGIRIS & EANRIS Poster Participant, EB 2009, New Orleans, LA, April 18-22, 2009

· Awarded First Place Prize, Experimental Animal Nutrition RIS Poster Competition, EB 2009, New Orleans, LA, April 18-22, 2009

 

April 2009                       York University Media Release

 

January 2009                 2009 Caroline tum Suden/Frances A. Hellebrandt Professional Opportunity Award.

Awarded by the American Physiological Society (APS).

To be presented at Experimental Biology 2009 (New Orleans, LA)

 

Sept 2007 – Apr 2008     Dean’s Honour List, York University

 

Sept 2006 – Apr 2007     Dean’s Honour List, University of Western Ontario

 

Sept 2005 – Apr 2006     Dean’s Honour List, University of Western Ontario

 

Sept 2004 – Apr 2005     Queen Elizabeth Aiming for the Top Scholarship

 

Sept 2003 – Apr 2004     Dean’s Honour List, University of Western Ontario

                                        Queen Elizabeth Aiming for the Top Scholarship

                                        University of Western Ontario Entrance Scholarship

 

June 2003                          Ontario Scholar

                                            Bilingual Certificate

 

 

EMPLOYMENT EXPERIENCE


Sept 2008 – Present                  Research Assistant

                                                      Supervisor: Dr. Lorne Zinman, ALS Research

                                                      Sunnybrook Health Sciences Centre, Toronto, ON

 

Sept 2008 – Present                  Teaching Assistant

                                                      Course: Nutritional Aids in Sport and Exercise (KINE 4120)

                                                   School of Kinesiology and Health Science, York University, Toronto, ON

 

Sept 2008 – Present                  Teaching Assistant

                                                      Course: Skilled Performance and Motor Learning (KINE 3020)

 

Sept 2007 – Present                  Research Assistant

                                                   Supervisor: Dr. Mazen J Hamadeh, Nutrition Laboratory

                                                   School of Kinesiology and Health Science, York University, Toronto, ON

 

Jul 2001- Present                      Private Academic Tutor                               

                                                   Toronto, ON

 

May 2006 – Aug 2007               Toronto Social Services – Summer Student Support Assistant

                                                   North York Central Social Services, City of Toronto, Toronto, ON

 

May 2005 – Aug 2005               Research Assistant

                                                   Study: Ortech Data Centre website patient research data record

London Health Sciences Centre, Department of Orthopaedic Research, University Hospital, London, ON

 

Sept 2004 – Apr 2005                Research Assistant

Study: Use of Hands Free Technique among surgeons and operating room nurses during various surgical procedures

University of Western Ontario, Department of Epidemiology and Biostatistics, London, ON

 

Sept 2004 – Dec 2004                Aquatics Instructor

Boys and Girls Club of London, London, ON

 

May 2004 – Aug 2004                Intellectual Property Department Summer Student

McCarthy Tétrault LLP, Department of Trademarks and Copy Rights, Toronto, ON

 

Aug 2002-Aug 2003                   Rehabilitation Assistant

Scarborough Physiotherapy and Rehab Clinic, Toronto, ON

 

Jan 2002 – Sept 2005                Aquatics Lifeguard and Instructor

City of Toronto Parks and Recreation, East District, Toronto, ON

 

Jul 2000 – Aug 2002                  Administrative Assistant

Century 21 Leading Edge Realty Inc., Toronto, ON

 

 

COMMITTEE MEMBERSHIPS

 

Sept 2007 – Present                  Kinesiology and Health Science GSA Treasurer

York University, Toronto, ON

 

Sept 2007 – Present                  Graduate Student Association member

York University, Toronto, ON

 

Sept 2006 – Apr 2007                VP Student Affairs, Kinesiology Student Council

                                                 University of Western Ontario, London, ON

 

Sept 2005 – Apr 2006                Kinesiology student representative, Kinesiology Student Council

University of Western Ontario, London, ON

 

 

ACADEMIC MEMBERSHIPS


2008   Canadian Society for Nutritional Sciences (CSNS)

 

2008   American Physiological Society (APS)

 

2008   American Society for Nutrition (ASN)

 

2007   Canadian Society for Exercise Physiology (CSEP)

 

2007   Canadian Personal Trainer Network (CPTN)

 

 

TECHNICAL SKILLS


Academic Research Skills: literature searches, writing reviews, podium presentations, poster presentations, seminar presentations, statistical analyses, manuscript preparations, research ethics preparations, provincial, national and international conference presentations

 

Animal Research Skills: mice handling and sacrifice, surgical removal of organ and muscle tissues

 

Laboratory Research Skills: lab maintenance (ordering chemicals and equipment), preparation of various buffers and solutions, pH titration, spectrophotometric enzyme assays, protein quantification and analysis, western blotting, imaging, lab supervisory

 

Clinical Research Skills: research ethics preparations, patient recruitment (informed consent), bioelectrical impedance analysis (BIA) measurements

 

 

VOLUNTEERING

 

June 2008                                 Researcher, ALS Neuromuscular Clinic

Sunnybrook Health Science Centre, Toronto, ON

 

Jul 2007                                    ALS Society of Ontario fundraiser: Blue Jays baseball game, Toronto, ON

 

Oct 2006                                       ALS Society of Ontario: WALK for ALS, London, ON

 

Sep 2006 – Apr 2007                 Kinnector (mentor) for first year kinesiology undergraduate students University of Western Ontario, London, ON

 

Sep 2005 – Apr 2007                 Child monitor for YMCA daycare, University of Western Ontario, University Community Centre, London, ON

 

Dec 2004 – Dec 2007                 Games coordinator and event organizer for Kinesiology Special Games for special needs children, University of Western Ontario, London, ON

 

 

EXTRACURRICULAR ACTIVITIES

 

Travelling independently: China, California, United Kingdom, Holland, Switzerland, France, Cuba

 

Mountain Climbing: Rochers De Naye (1810m, Switzerland);  Huangshan (1864m, China)

 

Recreational Fitness: cardiovascular and resistance training, fitness classes

 

Recreational Sports: swimming, volleyball, tennis, British netball

 

Nutrition, Fitness, and Health promotion

 

 

JOURNAL PUBLICATIONS


Seevaratnam R, Patel BP, Hamadeh MJ. Comparison of total protein concentration in skeletal muscle as measured by the Bradford and Lowry assays. J Biochem 2009;145:791–7 . Abstract

 

 

ABSTRACTS


Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Coffee, caffeine, and chlorogenic acid reduce oxidative stress and apoptosis, and improve antioxidant enzyme capacity in male G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). Proceedings of the CSCN-CSNS Annual Scientific Meeting 2009:138 (abst.).

 

Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Caffeine increases apoptosis and decreases antioxidant enzyme capacity, in spite of decreasing markers of oxidative stress in female G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). Proceedings of the CSCN-CSNS Annual Scientific Meeting 2009:276 (abst.).

 

Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Caffeine reduces motor performance and antioxidant enzyme capacity in the brain of female G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). FASEB J 2009;23:963.3 (abst.). Abstract

 

Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Coffee increases antioxidant enzyme capacity in the brain of male G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). FASEB J 2009;23:109.6 (abst.). Abstract

 

Seevaratnam R, Raha S, Tarnopolsky M, Hamadeh MJ. Coffee improves antioxidant capacity in male G93A mice, whereas caffeine reduces it in female G93A mice, an animal model of Amyotrophic lateral sclerosis (ALS). Proceedings of the Ontario Exercise Physiology Conference 2009:27 (abst.).

 

Seevaratnam R, Patel BP, Hamadeh MJ. The Bradford assay proves superior to the Lowry assay in determining protein concentration for comparison of nutrient protein interactions in skeletal muscle. Proceedings of the CSCN-CSNS Annual Scientific Meeting 2008:SUP14.

 

Seevaratnam R, Patel BP, Hamadeh MJ. Determination of protein concentration in skeletal muscle using two spectrophotometric assays: the Lowry and the Bradford. FASEB J 2008;22:LB252 (abst.). Abstract

 

Seevaratnam R, Patel BP, Hamadeh MJ. To Lowry or to Bradford: Validation of two spectrophotometric methods for the determination of protein concentration in skeletal muscle. Proceedings of the Ontario Exercise Physiology Conference 2008:26 (abst.).

 

 

INVITED TALKS

 

November 29, 2006        School of Kinesiology, University of Western Ontario

                                           “Amyotrophic Lateral Sclerosis: A Brief Review”

 

 

CONFERENCE PRESENTATIONS


Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Coffee, caffeine, and chlorogenic acid reduce oxidative stress and apoptosis, and improve antioxidant enzyme capacity in male G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). Canadian Society for Clinical Nutrition and Canadian Society of Nutritional Sciences Annual Scientific Conference, Quebec City, QC, May 30 - June 2, 2009 (oral presentation).

 

Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Caffeine increases apoptosis and decreases antioxidant enzyme capacity, in spite of decreasing markers of oxidative stress in female G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). Canadian Society for Clinical Nutrition and Canadian Society of Nutritional Sciences Annual Scientific Conference, Quebec City, QC, May 30 - June 2, 2009 (poster presentation).

 

Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Caffeine reduces motor performance and antioxidant enzyme capacity in the brain of female G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). Experimental Biology conference, New Orleans, LA, April 18-21, 2009 (poster presentation).

 

Seevaratnam R, Raha S, Tarnopolsky MA, Hamadeh MJ. Coffee increases antioxidant enzyme capacity in the brain of male G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). Experimental Biology conference, New Orleans, LA, April 18-21, 2009 (oral presentation).

 

Seevaratnam R, Raha S, Tarnopolsky M, Hamadeh MJ. Coffee and caffeine supplementation reduces markers of oxidative stress in male and female G93A mice, an animal model of amyotrophic lateral sclerosis (ALS). Ontario Exercise Physiology Conference, Barrie, ON, January 23-25, 2009 (podium presentation).

 

Seevaratnam R, Patel BP, Hamadeh MJ. The Bradford Assay Proves Superior to the Lower Assay in Determining Protein Concentration for Comparison of Nutrient Protein Interactions in Skeletal Muscle. Canadian Society for Clinical Nutrition and Canadian Society of Nutritional Sciences joint conference, Toronto, ON, May 29 - 31, 2008 (poster presentation).

 

Seevaratnam R, Patel BP, Hamadeh MJ. Determination of protein concentration in skeletal muscle using two spectrophotometric assays: the Lowry and the Bradford. Experimental Biology conference, San Diego, CA, April 5-9, 2008 (poster presentation).

 

Seevaratnam R, Patel BP, Hamadeh MJ. To Lowry or to Bradford: validation of 2 spectrophotometric methods for the determination of protein concentration in skeletal muscle. Ontario Exercise Physiology conference, Barrie, ON, January 25-27, 2008 (podium presentation).

 

 

MANUSCRIPTS IN PREPARATION

 

Seevaratnam R, Hamadeh MJ. The effects of coffee, caffeine, and chlorogenic acid supplementation on molecular outcome measures of oxidative stress and apoptosis in brain tissue of Cu/Zn SOD1 mutant G93A mice, an animal model of Amyotrophic Lateral Sclerosis (ALS). Am J Clin Nutr. 2009.


 

 

 


 

 

Last updated: June 8, 2009