Wales S, Hashemi S, Blais A, McDermott JC. Global MEF2 target gene analysis in cardiac and skeletal muscle reveals novel regulation of DUSP6 by p38MAPK-MEF2 signaling. Nucleic Acids Res. 2014 Oct;42(18):11349-62. Significance of the research: The goal of our lab is to understand the role of transcription factor MEF2 during development and disease. MEF2 (A-D) […]
Thomas MM, Trajcevski KE, Coleman SK, Jiang M, Di Michele J, O'Neill HM, Lally JS, Steinberg GR, Hawke TJ. Early oxidative shifts in mouse skeletal muscle morphology with high-fat diet consumption do not lead to functional improvements. Physiol Rep. 2014 Sep 17;2(9). Significance of the research: The incidence of type 2 diabetes mellitus (T2DM) […]
Yardley JE, Zaharieva DP, Jarvis C, Riddell MC. The "Ups" and "Downs" of a Bike Race in People with Type 1 Diabetes: Dramatic Differences in Strategies and Blood Glucose Responses in the Paris-to-Ancaster Spring Classic. Can J Diabetes. 2015 Apr;39(2):105-10. Significance of the research: For individuals with type 1 diabetes, physical activity has numerous health […]
Exclusively access an Invited Review by Dr. David A. Hood, co-authored by Heather N. Carter and Chris C.W. Chen, entitled: "Mitochondria, Muscle Health and Exercise with Advancing Age." Click here to access the article.
The MHRC is proud to announce that two members of the Haas Lab have received travel awards to attend Experimental Biology (Boston, 2015) based on their abstract submissions. Emmanuel Nwadozi has received the Zweifach Student Award from the Microcirculatory Society, and Erin Mandel has received a Research Recognition Award from the Cardiovascular Section, American Physiological […]
Slopack D, Roudier E, Liu ST, Nwadozi E, Birot O, Haas TL. Forkhead BoxO transcription factors restrain exercise-induced angiogenesis. J Physiol. 2014 Sep 15;592(Pt 18):4069-82. Significance of the research: Aerobic exercise training induces numerous adaptations within muscle that facilitate enhanced performance. One such adaptation is a growth of new capillaries, which bring more oxygen and […]
Wu MV, Bikopoulos G, Hung S, Ceddia RB. Thermogenic capacity is antagonistically regulated in classical brown and white subcutaneous fat depots by high fat diet and endurance training in rats: impact on whole-body energy expenditure. J Biol Chem. 2014 Dec 5;289(49):34129-40. Significance of the research: Two types of adipose tissue are found in humans: white […]
In an interview with Maclean's magazine, McMaster University's Martin Gibala discussed the merits of high intensity interval training with respect to cardiovascular health and fitness. Click here for a link to the full article.
Iqbal S, Hood DA. Cytoskeletal regulation of mitochondrial movements in myoblasts. Cytoskeleton (Hoboken). 2014 Oct;71(10):564-72. Significance of the research: Our laboratory examines the movement of mitochondria, also affectionately known as “the powerhouse of the cell” due to its ability to produce energy that is required for the maintenance and health of the cell. Movement of […]
Jeganathan S, Abdullahi A, Zargar S, Maeda N, Riddell MC, Adegoke OA. Amino acid-induced impairment of insulin sensitivity in healthy and obese rats is reversible. Physiol Rep. 2014 Jul 4;2(7). pii: e12067. doi: 10.14814/phy2.12067. High protein diets are used as non-pharmacological interventions in the management of obesity and associated comorbidities. Also, such diets are beneficial […]