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Paper of the month (September 2021) from Dr. Olivier Birot and Dr. Pierre Lemieux

Lemieux Pierre, Birot Olivier. (2021). Altitude, Exercise, and Skeletal Muscle Angio-Adaptive Responses to Hypoxia: A Complex Story. Frontiers in Physiology, V12, p146. https://www.frontiersin.org/article/10.3389/fphys.2021.735557 Significance of the research: Hypoxia, defined as a reduced oxygen availability, can be observed in many tissues in response to various physiological and pathological conditions. As a hallmark of the altitude environment, […]

Paper of the month (June 2021) from Dr. John McDermott's research group

Miyake, T., Aziz, A., & McDermott, J. C. (2020). Maintenance of the Undifferentiated State in Myogenic Progenitor Cells by TGFβ Signaling is Smad Independent and Requires MEK Activation. International journal of molecular sciences, 21(3), 1057. https://doi.org/10.3390/ijms21031057 Significance of the research: Transforming growth factor β (TGFβ) is a pluripotent cytokine that has potent effects on skeletal […]

Paper of the month (May 2021) from Dr. Olasunkanme (Ola) Adegoke's research group

Mann, G., & Adegoke, O. (2021). Effects of ketoisocaproic acid and inflammation on glucose transport in muscle cells. Physiological reports, 9(1), e14673. https://doi.org/10.14814/phy2.14673 Significance of the research: Type 2 diabetes and cardiovascular diseases affect millions of people world-wide, with the attending implications for morbidity and mortality. An underlying cause of these diseases is insulin resistance, especially skeletal […]

Paper of the month (April 2021) from Dr. Ronald Ceddia's research group

Da Eira, D., Jani, S., Sung, H., Sweeney, G., & Ceddia, R. B. (2020). Effects of the adiponectin mimetic compound ALY688 on glucose and fat metabolism in visceral and subcutaneous rat adipocytes. Adipocyte, 9(1), 550–562. https://doi.org/10.1080/21623945.2020.1817230   Significance of the research: Adiponectin is an adipose-derived hormone that is significantly reduced in the blood of obese and type 2 diabetic […]