OICR Cancer Therapeutics Innovation Pipeline: Early Validation Projects

Details

Opportunity Name	Early Validation Projects
Agency	Ontario Institute for Cancer Research
Value	Up to $150,000/year
Indirect Costs	Eligible at 30%
Duration	Up to 2 years

Deadlines

Note: The deadline for submission of the Notice of Intent (NOI) is the same as the deadline for Letter of Intent (LOI) submission, however, applicants are encouraged to submit their NOI as early as possible to assist with planning and to ensure sufficient time to complete the LOI by the deadline. 

Information session	06-30-2022, 2:00 – 3:00PM
Letter of Intent (LOI) due to FSc RO at sciapps@yorku.ca for full review	06-28-2022
LOI and fully signed ORS checklist due to FSc RO at sciapps@yorku.ca for mandatory review	07-06-2022
Final LOI and fully signed ORS checklist due at ORS for mandatory review	07-11-2022, by 9:00AM
LOI due at agency	07-13-2022, by 5:00PM
Notice of Intent (NOI) submission	07-13-2022, by 5:00PM
Application due to FSc RO at sciapps@yorku.ca for full review	09-21-2022
Application and fully signed ORS checklist due to FSc RO at sciapps@yorku.ca for mandatory review	09-28-2022
Final application and fully signed ORS checklist due at ORS for mandatory review	10-03-2022, by 9:00AM
Application due at agency (by invitation only)	10-05-2022, by 5:00PM

Objective

Deliver robust translational evidence that a Target-of-Interest (TOI) is associated with a specific cancer type(s) based on data from knowledge bases and from studies demonstrating that perturbation of the TOI in relevant cell-based models produces anti-cancer effects sufficient to trigger a drug discovery campaign. 

The overall objectives of this program are to:

• Create a pipeline of validated cancer targets and first-in-class or best-in-class, novel, selective lead molecules (small molecules or biologics) that will attract partnerships and/or investment for further preclinical and clinical development; and
• Support projects that aim to provide increasing evidence of target validation and disease association using data from knowledge bases, functional assays, and drug screening in relevant in vitro and in vivo models of the cancer type of interest. 

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Eligibility

• OICR invites applications from investigators at Ontario academic centres, hospital research institutes or other government research institutions. CTIP funding is only tenable in Ontario.
  • For profit entities are not eligible to receive CTIP funding.
• Investigators are eligible to participate on and submit multiple CTIP submissions via this RFA.

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How to Apply

York University researchers are reminded that all applications for external research funding, including Letters of Intent, must be reviewed and approved by the Office of Research Services before they are submitted to the granting agency.  For internal approval, the application must be accompanied by a completed ORS Checklist, which requires the Dean’s signature.  Please send the complete application, with the finalized budget and a completed ORS checklist to sciapps@yorku.ca, five days prior to agency deadline.

ORS is accepting electronic applications – the process is outlined here.

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Information Session

An information session will be held on June 30, 2022 from 2:00 – 3:00PM.

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For specific questions, please contact your FSc Research Officer