Writing about our research

  • Lowe, D. The Good Stuff Goes One Way. . . IN THE PIPELINE, 6 February 2019. (Online)
  • Fellet, M. Chromatography method measures protein-small molecule interactions. Chemical & Engineering News, 14 October 2014. (Online) (PDF file)
  • Noris, V. Faculty of 1000, 3 September 2013. (Online)
  • Silverman, S.K. Faculty of 1000 Biology, 17 September 2010. (Online) (PDF file)
  • Evans, J. All in the mix. SeparationNow, 15 September 2008. (Online) (PDF file)
  • Burks, R. Aptamer trio bests antibodies in quantifying protein over wide concentration range. Chemical & Engineering News, 18 June 2007, 85(25), 14. (Online) (PDF file)
  • Evans, J. Kinetic capillary electrophoresis separates compounds in a bind. SeparationNow, 19 February 2006. (Online) (PDF file)
  • Sidawi, D. Researchers seek to harness the power of stem cells. R&D Magazine, April 2005, 18–21. (PDF file)
  • Davvis, B.  Unraveling cellular biochemistry, one cell at a time. The Scientist 2005, 19(4), 27–29. (Online) (PDF file)
  • Mukhopadhyay, R. Aptamers are ready for. Analytical Chemistry 2005, 77, 115A–118A. (Online) (PDF file)
  • Payne, D. Toward a diagnostic Swiss army knife. The Scientist 2004, 18(22), 36. (Online) (PDF file)

Useful reviews

  • Galievsky, V.A. et al. Capillary electrophoresis in quantitative studies of biomolecular interactions. Analytical Chemistry 2015, 87, 157–171. (PDF file)
  • Krylov, S.N. Direct quantitative analysis of multiple miRNAs (DQAMmiR) - a new tool for personalized cancer medicine. Laboratory Focus, July 2012, 10–12. (PDF file)
  • Krylova, S.M. et al. Transverse diffusion of laminar flow profiles - a generic method for mixing reactants in capillary microreactor. Journal of Separation Science 2009, 32, 742–756. (PDF file)
  • Krylov, S.N. Aptamer-facilitated biomarker disovery. Laboratory Focus 2008, July, 12–14. (Online) (PDF file)
  • Krylov, S.N. Kinetic capillary electrophoresis: foundation for homogeneous kinetic affinity methods. Electrophoresis 2007, 28, 69–88. (PDF file)
  • Krylov, S.N. Non-equilibrium capillary electrophoresis of equilibrium mixtures (NECEEM): a novel method for biomolecular screening. Journal of Biomolecular Screening 2006, 11, 115–122. (PDF file)
  • Krylov, S.N. NECEEM for development, characterization and analytical utilization of aptamer. LabPlus International, November 2005, 6–9. (PDF file)

Publications - Refereed Journals

• - high impact publications.

2024

208. Wang, T.Y.; Bijlani, A.; Kaiyum, Y.A., Krylova, S.M.; Johnson, P.E.; Krylov, S.N. Introducing Accuracy Confidence Interval (ACI) for Equilibrium Constants Determined with Isothwermal Titration Calorimetry. Under development.

207. Schreiber, S.; Krylov, S.N. Assessing Probability Distribution for Accurate Equilibrium Dissociation Constants (Kd) Using the Accuracy Confidence Interval (ACI) of Kd. Under development.

206. Wang, T.Y.; Dhillon, P.; Schreiber, S.; Krylova, S.M.; Golemi-Kotra D.; Krylov, S.N. Introducing Quantitative Assessment of Michaelis Constant (KM) Accuracy. Under development.

205. Panferov, V.G.; Ivanov, N.A.; Krylov, S.N. Visual and instrumental registration of colorimetric signals in lateral flow immunoassay in hemolyzed samples. Under development.

204. Panferov, V.G.; Ivanov, N.A.; Krylov, S.N. Exploring the thermal profile of nitrocellulose membrane during electrophoresis-driven paper assay. Analytical Chemistry. Under development.

203. Che, X.; Ivanov, N.A.; Krylova, S.M.; Krylov, S.M. Single-Reservoir Electrophoresis to Facilitate Layer-by-Layer Assembly of Gold Nanoparticles in Lateral Flow Immunoassay. Under revision.

202. Wang, T.Y.; Latimer, J.; Rukundo, J.-L.; Kogan, I.; Krylova, S.M.; Schreiber, S.; Kohlmann, P.; Jose, J.; Krylov, S.N. A Practical Approach to Quantitatively Assessing Equilibrium-Constant Accuracy from a Single Binding Isotherm. Precision Chemistry. Accepted (ChemRxiv)

201. Le, A.T.H.; Teclemichael, E.; Krylova, S.M.; Krylov, S.N. Quantitative Characterization of Partitioning Stringency in SELEX. Under revision (ChemRxiv)

200. Wang, T.Y.; Rukundo, J.-L.; Mao, Z.; Krylov, S.N. Maximizing the Accuracy of Equilibrium Dissociation Constants for Affinity Complexes: From Theory to Practical Recommendations. ACS Chemical Biology 2024, 19(9), 1852–1867. (Online)

199. Van Riesen, A.J.; Regan, K.T.; Kalnitsky, B.; Shoara, A.A.; Slavkovic, S.; Churcher, Z.R.; Johnson, P.E.; Nebbioso, G.; Krylov, S.N.; Manderville, R.A. Tuning Phenolic Hemicyanines for Ratiometric DNA Sensing and Live Cell Nuclear Bioimaging Applications. Canadian Journal of Chemistry 2024. (Online).

198. Krylov, S.N. Underestimation of the Complexity of Kd Determination: Causes, Implications, and Ways to Improve. ACS Measurement Science Au 2024, 4(3), 231–232. (Online)

197. Kohlmann, P.; Krylov, S.N.; Marchand, P.; Jose, J. FRET assays for the identification of C. albicans HSP90-Sba1 and human HSP90α-p23 binding inhibitors. Pharmaceuticals 2024, 17(4), 516. (Online)

196. Ivanov, N.A.; Panferov, V.G.; Krylov, S.N. A Nonsteady-State Electric Circuit in Electrophoresis on Paper: Thermal Consideration of Electrophoretic Lateral-Flow Assays. Analytical Chemistry 2024, 96(7), 3217–3222. (Online)

2023

195. Wang, T.Y.; Ji, W.; Evetron, D.; Le, A.T.H.; Krylova, S.M.; Fournier, R.; Krylov, S.N. Fundamental Determinants of the Accuracy of Equilibrium Constants for Affinity Complexes. Analytical Chemistry 2023, 95(42), 15826–15832. (Online) (PDF file)

194. Norris, V.; Oláh, J.; Krylov, S.N.; Uversky, V.N.; Ovádi, J. The Sherpa hypothesis: Phenotype-Preserving- Disordered Proteins stabilize the phenotypes of neurons and oligodendrocytes. npj Systems Biology and Applications 2023, 31. (PDF file)

193. Nebbioso, G.; Yosief, R.; Koshkin, V.; Qiu, Y.; Peng, C.; Elisseev, V.; Krylov, S.N. Automated identification and tracking of cells in cytometry of reaction rate constant (CRRC). PLoS ONE 2023, 18(7), e0282990. (Online) (PDF file)

192. Panferov, V.G.; Ivanov, N.A.; Brinc, D.; Fabros, A.; Krylov, S.N. Electrophoretic Assembly of Antibody-Antigen Complexes Facilitates 1000 Times Improvement in the Limit of Detection of Serological Paper-Based Assay. ACS Sensors 2023, 8(4), 1792–1798. (Online) (PDF file)

191. Le, A.T.H.; Krylova, S.M.; Krylov, S.N. Kinetic capillary electrophoresis in screening oligonucleotide libraries for protein binders. TrAC – Trends in Analytical Chemistry, 2023, 162, 117061. (Online) (PDF file)

190. Rukundo, J.-L.; Latimer, J.; Jain, S.; Kochmann, S.; Krylov, S.N. Streamlined Data Processing for Determination of Dissociation Constants with Accurate Constant via Transient Incomplete Separation (ACTIS). Analytical Chemistry 2023, 95(7), 3563–3568. (PDF file)

189. Panferov, V.G.; Ivanov, N.A.; Mazzulli, T.; Brinc, D.; Kulasingam, V.; Krylov, S.N. Electrophoresis-assisted multilayer assembly of nanoparticles for sensitive later-flow immunoassay. Angewandte Chemie International Edition 2023, 62(2), e202215548. (Online) (PDF file)

2022

188. Teclemichael, E.; Le, A.T.H.; Krylova, S.M.; Wang, T.Y.; Krylov, S.N. Bulk Affinity Assays in Aptamer Selection: Challenges, Theory, and Workflow. Analytical Chemistry 2022, 94(44), 15183–15188. (PDF file)

187. Wang, T.Y.; Ivanov, N.A.; Rukundo, J.-L.; Le Blanc, J.C.Y.; Gorin, B.I. Krylov, S.N. Transient Incomplete Separation of Species with Close Diffusivity to Study Stability of Affinity Complexes. Analytical Chemistry 2022, 94(44), 15415–15422. (PDF file)

186. Kochmann, S.; Ivanov, N.A.; Le Blanc J.C.Y.; Gorin, B.I.; Krylov, S.N. Circular Geometry in Molecular Stream Separation to Facilitate Nonorthogonal Field-to-Flow Orientation. Analytical Chemistry 2022, 94(27), 9519–9524. (PDF file)

185. Le, A.T.H.; Wang, T.Y.; Krylova, S.M.; Beloborodov, S.S.; Krylov, S.N. Quantitative Characterization of Partitioning in Selection of DNA Aptamers for Protein Targets by Capillary Electrophoresis. Analytical Chemistry 2022, 94(5), 2578–2588. (PDF file)

2021

184. Kochmann, S.; Ivanov, N.A.; Lucas, K.S.; Krylov, S.N. Topino: A Graphical Tool for Quantitative Assessment of Molecular Stream Separations. Analytical Chemistry 2021, 93(29), 9980–9985. (PDF file)

183. Rukundo, J.-L.; Kochmann, S.; Wang, T.Y.; Ivanov, N.A.; Le Blanc, J.C.Y.; Gorin, B.I. Krylov, S.N. Template Instrumentation for “Accurate Constant via Transient Incomplete Separation” (ACTIS). Analytical Chemistry 2021, 93(34), 11654–11659. (Online)

182. Koshkin, V.; Bleker de Oliveira, M.; Peng, C.; Ailles, L.E.; Liu, G.; Covens, A.; Krylov, S.N. Multi-drug-resistance efflux in cisplatin-naive and cisplatin-exposed A2780 ovarian cancer cells responds differently to cell culture dimensionality. Molecular and Clinical Oncology 2021, 15, 161. (Online)

181. Le, A.T.H.; Krylova, S.M.; Beloborodov, S.S.; Wang, T.Y.; Hili, R.; Johnson, P.E.; Li, F.; Veedu, R.N.; Belyanskaya, S.; Krylov, S.N. How to Develop and Prove High-Efficiency Selection of Ligands from Oligonucleotide Libraries: A Universal Framework for Aptamers and DNA-Encoded Small-Molecule Ligands. Analytical Chemistry 2021, 93(13), 5343–5354. (PDF file)

2020

180. Hu, L.; Krylova, S.M.; Liu, S.K.; Yousef, G.M.; Krylov, S.N. Necessity and Challenges of Sample Pre-concentration in Analysis of Multiple MicroRNAs by Capillary Electrophoresis. Analytical Chemistry 2020, 92, 14251–14258. (Online)

179. Bleker de Oliveira, M.; Koshkin, V.; Liu, G.; Krylov, S.N. Analytical Challenges in Development of Chemoresistance Predictors for Precision Oncology. Analytical Chemistry 2020, 92, 12101–12110. (Online)

178. Rukundo, J.-L.; Le Blanc, J.C.Y.; Kochmann, S.; Krylov, S.N. Assessing Accuracy of an Analytical Method in silico: Application to “Accurate Constant via Transient Incomplete Separation” (ACTIS). Analytical Chemistry 2020, 92, 11973–11980. (PDF file)

177. Koshkin, V.; Bleker de Oliveira, M.; Peng, C.; Ailles, L.E.; Liu, G.; Covens, A.; Krylov, S.N. Spheroid-Based Approach to Assess Tissue Relevance of Analysis of Dispersed-Settled Tissue Cells by Cytometry of Reaction Rate Constant. Analytical Chemistry 2020, 92, 9348–9355. (Online)

176. Wang, T.Y.; Hu, L.; Krylov, S.N. Empirical Predictor of Conditions which Support Ideal-Filter Capillary Electrophoresis. Electrophoresis 2020, 41, 1225–1229. (PDF file)

175. Ivanov, N.A.; Kochmann, S.; Krylov, S.N. Visualization of Streams of Small Organic Molecules in Continuous-Flow Electrophoresis. Analytical Chemistry 2020, 92, 2907–2910. (PDF file)

2019

174. Beloborodov, S.S.; Krylova, S.M.; Krylov, S.N. Spherical-shape assumption for protein–aptamer complexes facilitates prediction of their electrophoretic mobility. Analytical Chemistry 2019, 91, 12680–12687. (PDF file)

173. Le, A.T.H.; Krylova, S.M.; Krylov, S.N. Determination of the equilibrium constant and rate constant of protein–oligonucleotide complex dissociation under the conditions of ideal-filter capillary electrophoresis. Analytical Chemistry 2019, 91, 8532–8539. (PDF file)

172. Ivanov, N.A.; Liu, Y.; Kochmann, S.; Krylov, S.N. Non-aqueous continuous-flow electrophoresis (NACFE): separation complement for continuous-flow organic synthesis. Lab on Chip 2019, 19, 2156–2160. (PDF file)

171. Sisavath, N.; Rukundo, J.-L.; Le Blanc, J.C.Y.; Galievsky, V.; Bao, J.; Kochmann, S.; Stasheuski, A.S.; Krylov, S.N. Transient incomplete separation facilitates finding accurate equilibrium dissociation constant of protein–small molecule complex. Angewandte Chemie International Edition 2019, 58, 6635–6639. (PDF file)

170. Le, A.T.H.; Krylova, S.M.; Krylov, S.N. Ideal-filter capillary electrophoresis (IFCE): a highly efficient partitioning method for selection of protein binders from oligonucleotide libraries. Electrophoresis 2019, 40, 2553–2564. (PDF file)

169. Koshkin, V.; Kochmann, S.; Sorupanathan, A.; Peng, C.; Ailles, L.E.; Liu, G.; Krylov, S.N. Cytometry of reaction rate constant: measuring reaction rate constant in individual cells to facilitate robust and accurate analysis of cell-population heterogeneity. Analytical Chemistry 2019, 91, 4186–4194. (PDF file)

168. Le, A.T.H.; Krylova, S.M.; Kanoatov, M.; Desai, S.; Krylov, S.N. Ideal-filter capillary electrophoresis (IFCE) facilitates the one-step selection of aptamers. Angewandte Chemie International Edition 2019, 58, 2739–2743. (PDF file)

2018

167. Hu, L.; Anand, M.; Krylova, S.M.; Yang, B.B.; Liu, S.K.; Yousef, G.M.; Krylov, S.N. Direct quantitative analysis of multiple microRNAs (DQAMmiR) with peptide nucleic acid hybridization probes. Analytical Chemistry 2018, 90, 14610–14615. (PDF file)

166. Kochmann, S.; Le, A.T.H.; Hili, R.; Krylov, S.N. Predicting efficiency of NECEEM-based partitioning of protein binders from non-binders in DNA-encoded libraries. Electrophoresis 2018, 39, 2991–2996. (PDF file)

165. Kochmann, S.; Krylov, S.N. Quantitative characterization of molecular-stream separation. Analytical Chemistry 2018, 90, 9504–9509. (PDF file)

164. Du, W.W.; Yang, W.; Li, X.; Awan, F,M.; Yang, Z.; Fang, L.; Lyu, J.; Li, F.; Peng, C.; Krylov, S.N.; Xie, Y.; Zhang, Y.; He, C.; Wu, N.; Zhang, C.; Sdiri, M.; Dong, J.; Ma, J.; Gao, C.; Hibberd, C.; Yang, B.B. A circular RNA circ-DNMT1 enhances breast cancer progression by activating autophagy. Oncogene 2018, 37, 5829–5842. (PDF file)

163. Salem, M.; O’Brien, J.; Bernaudo, S.; Shawer H.; Ye, G.; Brkic, J.; Amleh, A.; Vanderhyden, B.; Refky, B.; Yang B.B.; Krylov, S.N.; Peng, C. MicroRNA-590-3p promotes ovarian cancer growth and metastasis via a novel FOXA2-Versican pathway. Cancer Research 2018, 78, 4175–4190. (PDF file)

162. Beloborodov, S.S.; Bao, J.; Krylova, S.M.; Shala-Lawrence, A.; Johnson, P.E.; Krylov, S.N. Aptamer facilitated purification of functional proteins. Journal of Chromatography B 2018, 1073, 201–206. (PDF file)

2017

161. Shala-Lawrence, A.; Decker, M.J.; Krylova, S.M.; Gangopadhyay, S.S.; Beloborodov, S.S.; Hougland, J.L.; Krylov, S.N. Simultaneous analysis of non-lipidated protein and its lipidated counterpart: enabling quantitative investigation of protein lipidation's impact on cellular regulation. Analytical Chemistry 2017, 89, 13502–13507. (PDF file)

160. Galievsky, V.A.; Stasheuski, A.S.; Krylov, S.N. Improvement of LOD in fluorescence detection with spectrally non-uniform background by optimization of emission filtering. Analytical Chemistry 2017, 89, 11122–11128. (PDF file)

159. Shala-Lawrence, A.; Beheshti, S.; Newman, E.; Tang, M.; Krylova, S.M.; Leach, M.; Carpick, B.; Krylov, S.N. High-precision quantitation of a tuberculosis vaccine antigen with capillary-gel electrophoresis using an injection standard for consideration. Talanta 2017, 175, 273–279. (PDF file)

158. Khella, H.W.Z.; Daniel, N.; Youssef, L.; Scorilas, A.; Nofech-Mozes, R.; Mirham, L.; Krylov, S.N.; Lianidou, E.; Krizova, A.; Finelli, A.; Cheng, Y.; Yousef, G.M. Mir-10b is a prognostic marker in clear cell renal cell carcinoma. Journal of Clinical Pathology 2017, 70, 854–859. (Link to paper)

157. Vass, J.; Krylov, S.N. A fast stable discretization of the constant-convection-diffusion-reaction equations of Kinetic Capillary Electrophoresis (KCE). Applied Numerical Mathematics 2017, 122, 82–91. (PDF file)

156. Hu, L.; Stasheuski, A.S.; Wegman, D.W.; Wu, N.; Yang, B.B.; Hayder, H.; Peng, C.; Liu, S.K.; Yousef, G.M.; Krylov, S.N. Accurate miRNA analysis in crude cell lysate by capillary electrophoresis-based hybridization assay in comparison with quantitative reverse transcription-polymerase chain reaction. Analytical Chemistry 2017, 89, 4743–4748. (PDF file)

155. Norris, V.; Krylov, S.N.; Agarwal, P.K.; White, G.J. Synthetic, switchable enzymes. Journal of Molecular Microbiology and Biotechnology 2017, 27, 117–127. (PDF file)

154. Kochmann, S.; Krylov, S.N. Image processing and analysis system for development and use of free flow electrophoresis chips. Lab on Chip 2017, 17, 256–266. (PDF file)

153. Koshkin, V.; Ailles, L.E.; Liu, G.; Krylov, S.N. Preservation of the 3D phenotype upon dispersal of cultured cell spheroids into monolayer cultures. Journal of Cellular Biochemistry 2017, 118, 154–162. (PDF file)

2016

152. Beloborodov, S.S.; Panferov, V.G.; Safenkova, I.V.; Krylova, S.M.; Dzantiev, B.B.; Krylov, S.N. Unexpected electrophoretic behaviour of complexes between rod-like virions and bivalent antibodies. Analytical Chemistry 2016, 88, 11908–11912. (PDF file)

151. Kanoatov, M.; Mehrabanfar, S.; Krylov, S.N. Systematic approach to optimization of experimental conditions in nonequilibrium capillary electrophoresis of equilibrium mixtures. Analytical Chemistry 2016, 88, 9300–9308. (PDF file)

150. Kochmann, S.; Agostino, F.; LeBlanc, J.C.Y.; Krylov, S.N. The hyphenation of production-scale free-flow electrophoresis to electrospray ionization mass spectrometry using a highly conductive background electrolyte. Analytical Chemistry 2016, 88, 8415–8420. (PDF file)

149. Galievsky, V.A.; Stasheuski, A.S.; Krylov, S.N. "Getting the best sensitivity from on-capillary fluorescence detection in capillary electrophoresis" - A tutorial. Analitica Chimica Acta 2016, 935, 58–81. (PDF file)

148. Kanoatov, M.; Krylov, S.N. Analysis of DNA in phosphate buffered saline using kinetic capillary electrophoresis. Analytical Chemistry 2016, 88, 7421–7428. (PDF file)

147. Bao, J.; Krylova, S.M., Cherney, L.T.; Hale, R.L.; Belyanskaya, S.L.; Chiu, C.H.; Shaginian, A.; Arico-Muendel, C.C.; Krylov, S.N. Predicting electrophoretic mobility of protein-ligand complexes for ligands from DNA-encoded libraries of small molecules. Analytical Chemistry 2016, 88, 5498–5506. (PDF file)

146. Cherney, L.T.; Krylov, S.N. Slow-equilibration approximation in kinetic size exclusion chromatography. Analytical Chemistry 2016, 88, 4063–4070. (PDF file)

145. Du, W.W.; Yang, W.; Xuan, J.; Krylov, S.N.; Ma, X.; Yang, Q.; Khorshidi, A.; Yang, B.B. Reciprocal regulation of miRNAs and piRNAs in embryonic development. Cell Death and Differentiation 2016, 23, 1458–1470. (PDF file)

144. Nofech-Mozes, R.; Khella, H.W.Z.; Scorilas, A.; Youssef, L.; Krylov, S.N.; Lianidou, E.; Sidiropoulos, K.; Gabril, M.; Evans, A.; Yousef, G.M. MicroRNA-194 is a marker for good prognosis in clear cell renal cell carcinoma. Cancer Medicine 2016, 5, 656–664. (PDF file)

143. Butz, H.; Nofech-Mozes, R.; Ding, Q.; Khella, H.W.Z.; Szabo, P.; Jewett, M.; Finelli, A.; Lee, J.; Ordon, M.; Stewart, R.; Krylov, S.N.; Yousef, G.M. Exosomal miRNAs are diagnostic biomarkers and can mediate cell-cell communication in renal cell carcinoma. European Urology Focus 2016, 2, 210–218. (PDF file)

142. Wegman, D.W.; Ghasemi, F.; Stasheuski, A.S.; Khorshidi, A.; Yang, B.B.; Liu, S.K.; Yousef, G.M.; Krylov, S.N. Achieving single-nucleotide specificity in direct quantitative analysis of multiple microRNAs (DQAMmiR). Analytical Chemistry 2016, 88, 2472–2477. (PDF file)

141. Koshkin, V.; Ailles, L.E.; Liu, G.; Krylov, S.N. Metabolic suppression of a drug resistant subpopulation in cancer spheroid cells. Journal of Cellular Biochemistry 2016, 117, 59–65. (PDF file)

2015

140. Huang, X.; Taeb, S.; Jahangiri, S.; Korpela, E.; Cadonic, I.; Yu, N.; Fokas, E.; Krylov, S.N.; Boutros, P.; Liu, S.K. miR-620 promotes tumor radioresistance by targeting 15-hydroxyprostaglandin dehydrogenase (HPGD). Oncotarget 2015, 6, 22439–224351. (PDF file)

139. Du, W.W.; Liu, F.; Shan, S.W.; Ma, X.C., Gupta, S.; Jin, T.; Snaper, D.; Krylov, S.N.; Zhang, Y.; Ling, W.; Yang, B.B. Inhibition of dexamethasone-induced fatty liver development by reducing miR-17-5p levels. Molecular Therapy 2015, 23, 1222–1233. (PDF file)

138. Agostino, F.; Krylov, S.N. Advances in steady-state continuous-flow purification by small-scale free-flow electrophoresis. TrAC — Trends in Analytical Chemistry 2015, 72, 68–79. (PDF file)

137. Cherney, L.T.; Krylov, S.N. Slow-equilibration approximations in studying kinetics of protein adsorption on capillary walls. Analyst 2015, 140, 2797–2803. (PDF file)

136. Kanoatov, M.; Galievsky, V.A.; Krylova, S.M.; Cherney, L.T.; Jankowski, H.K.; Krylov, S.N. Using non-equilibrium capillary electrophoresis of equilibrium mixtures (NECEEM) for simultaneous determination of concentration and equilibrium constant. Analytical Chemistry 2015, 87, 3099–3106. (PDF file)

135. Khella, H.W.Z.; Scorilas, A.; Mozes, R.; Mirham, L.; Lianidou, E.; Krylov, S.N.; Lee, J.Y.; Ordon, M.; Stewart, R.; Jewett, M.; Yousef, G.M. Low expression of miR-126 is a prognostic marker for metastatic clear cell renal cell carcinoma. American Journal of Pathology 2015, 185, 693–703. (PDF file)

134. Bao, J.; Krylova, S.M.; Cherney, L.T.; Le Blanc, J.C.Y.; Pribil, P.; Johnson, P.E.; Wilson, D.J.; Krylov, S.N. Pre-equilibration kinetic size-exclusion chromatography with mass spectrometry detection (peKSEC-MS) for label-free solution-based kinetic analysis of protein-small molecule interactions. Analyst 2015, 140, 990–994. (PDF file)

133. Bao, J.; Krylova, S.M., Cherney, L.T.; Hale, R.L.; Belyanskaya, S.L.; Chiu, C.H.; Arico-Muendel, C.C.; Krylov, S.N. Prediction of protein-DNA complex mobility in gel-free capillary electrophoresis. Analytical Chemistry 2015, 87, 2474–2479. (PDF file)

132. Yufa, R.; Krylova, S.M., Bruce, C.; Bagg, E.A.; Schofield, C.J.; Krylov, S.N. Emulsion PCR significantly improves NECEEM-based aptamer selection, allowing for efficient and rapid selection of aptamer to unmodified ABH2 protein. Analytical Chemistry 2015, 87, 1411–1419. (PDF file)

131. Wegman, D.W.; Ghasemi, F.; Khorshidi, A.; Yang, B.B.; Liu, S.K.; Yousef, G.M.; Krylov, S.N. Highly-sensitive amplification-free analysis of multiple miRNAs by combining capillary isotachophoresis and electrophoresis. Analytical Chemistry 2015, 87, 1404–1410. (PDF file)

130. Cherney, L.T.; Petrov, A.P.; Krylov, S.N. One-dimensional approach to study kinetics of reversible adsorption of protein on capillary walls. Analytical Chemistry 2015, 87, 1219–1225. (PDF file)

129. Samaan, S.; Khella, H.W.Z.; Girgis, A.; Scorilas, A.; Lianidou, E.; Gabril, M.; Krylov, S.N. Jewett, M.; Bjarnason, G.A.; El-said, H.; Yousef, G.M. miR-210 is a prognostic marker in clear cell renal cell carcinoma. Journal of Molecular Diagnostics 2015, 17, 136–144. (PDF file)

128. Galievsky, V.A.; Stasheuski, A.S.; Krylov, S.N. Capillary electrophoresis for quantitative studies of biomolecular interactions. Analytical Chemistry 2015, 87, 157–171. (PDF file)

2014

127. Bao, J.; Krylova, S.M.; Cherney, L.T.; Le Blanc, J.C.Y.; Pribil, P.; Johnson, P.E.; Wilson, D.J.; Krylov, S.N. Kinetic size-exclusion chromatography with mass spectrometry detection (KSEC-MS): an approach for solution-based label-free kinetic analysis of protein-small molecule interactions. Analytical Chemistry 2014, 86, 10016–10020. (PDF file)

126. Agostino, F.; Cherney, L.T.; Kanoatov, M.; Krylov, S.N. Reducing pH gradients in free-flow electrophoresis. Analytical Chemistry 2014, 86, 5656–5660. (PDF file)

125. Kanoatov, M.; Cherney, L.T.; Krylov, S.N. Extracting kinetics from affinity capillary electrophoresis (ACE) data: a new blade for the old tool. Analytical Chemistry 2014, 86, 1298–1305. (PDF file)

2013

124. Liyanage, R.; Krylova, S.M.; Krylov, S.N. Minimizing adsorption of histidine-tagged proteins for the study of protein-DNA interactions by kinetic capillary electrophoresis. Journal of Chromatography A 2013, 1322, 90–94. (PDF file)

123. Musheev, M.U.; Kanoatov, M.; Retif, C.; Krylov, S.N. Stable DNA aggregation by removal of counterions. Analytical Chemistry 2013, 85, 10004–10007. (PDF file)

122. Ghasemi, F.; Wegman, D.W.; Kanoatov, M.; Yang, B.B.; Liu, S.K.; Yousef, G.M.; Krylov, S.N. Improvements to direct quantitative analysis of multiple microRNAs facilitating faster analysis. Analytical Chemistry 2013, 85, 10062–10066. (PDF file)

121. Koshkin, V.; Yang, B.; Krylov, S.N. Kinetics of MDR transport in tumor-initiating cells. PLoS ONE 2013, 8, e79222. (PDF file)

120. Wegman, D.W.; Cherney, L.T; Yousef, G.; Krylov, S.N. Universal drag tag for direct quantitative analysis of multiple microRNAs. Analytical Chemistry 2013, 85, 6518–6523. (PDF file)

119. Musheev, M.U.; Kanoatov, M.; Krylov, S.N. Non-uniform velocity of DNA in a uniform electric field: the consequence of electric-field-induced slow dissociation of highly-stable DNA-counterion complexes. Journal of the American Chemical Society 2013, 135, 8041–8046. (PDF file)

118. Koshkin, V.; Krylov, S.N. Single-cell-kinetics approach to discover functionally distinct subpopulations within phenotypically uniform populations of cells. Analytical Chemistry 2013, 85, 2578–2581. (PDF file)

117. Cherney, L.T.; Obrecht, N.M.; Krylov, S.N. Theoretical modeling of masking DNA application in aptamer-facilitated biomarker discovery. Analytical Chemistry 2013, 85, 4157–4164. (PDF file)

116. Agostino, F.J.; Cherney, L.T.; Galievsky, V.; Krylov, S.N. Steady-state continuous-flow purification by electrophoresis. Angewandte Chemie International Edition 2013, 52, 7256–7260. (PDF file)

115. Wegman, D.W.; Krylov, S.N. Direct miRNA-hybridization assays and their potential in diagnostics. Trends in Analytical Chemistry 2013, 44, 121–130. (PDF file)

114. Cherney, L.T.; Krylov, S.N. Theoretical estimation of drag tag lengths for direct quantitative analysis of multiple miRNAs (DQAMmiR). Analyst 2013, 138, 553–558. (PDF file)

2012

113. Mazouchi, A.; Dodgson, B.J.; Wegman, D.W.; Krylov, S.N.; Gradinaru, C.C. Ultrasensitive on-column laser-induced fluorescence in capillary electrophoresis using multiparameter confocal detection. Analyst 2012, 137, 5538–5545. (PDF file)

112. Bao, J.; Krylov, S.N. Volatile kinetic capillary electrophoresis for studies of protein-small molecule interactions. Analytical Chemistry 2012, 84, 6944–6947. (PDF file)

111. de Jong, S.; Epelbaum, N.; Liyanage, R.; Krylov, S.N. A semi-permanent coating for preventing protein adsorption in kinetic capillary electrophorsis. Electrophoresis 2012, 33, 2584–2590. (PDF file)

110. Koshkin, V.; Krylov, S.N. Correlation between multi-drug resistance-associated membrane transport in clonal cancer cells and the cell cycle phase. PLoS ONE 2012, 7, e41368. (PDF file)

109. Dodgson, B.J.; Mazouchi, A.; Wegman, D.W.; Gradinaru, C.C.; Krylov, S.N. Detection of a thousand copies of miRNA without enrichment or modification. Analytical Chemistry 2012, 84, 5470–5474. (PDF file)

108. Krylova, S.M.; Koshkin, V.; Bagg, E.; Schofield, C.J.; Krylov, S.N. Mechanistic studies on the application of DNA aptamers as Inhibitors of 2-oxoglutarate-dependent oxygenase. Journal of Medicinal Chemistry 2012, 55, 3546–3552. (PDF file)

107. Cherney, L.T.; Krylov, S.N. Two-peak approximation in kinetic capillary electrophoresis. Analyst 2012, 137, 1649–1655. (PDF file)

106. Cherney, L.T.; Okhonin, V.; Petrov, A.P.; Krylov, S.N. Sequential-dissociation kinetics of non-covalent complexes of DNA with multiple proteins in separation-based approach: General theory and its application. Analytica Chimica Acta 2012, 724, 111–118. (PDF file)

105. Patel, K.H.; Evenhuis, C.J.; Cherney, L.T.; Krylov, S.N. Simplified universal method for determining electrolyte temperatures (SUMET) in a capillary electrophoresis instrument with forced-air cooling. Electrophoresis 2012, 33, 1079–1085. (PDF file)

104. Woon, E.C.Y.; Demetriades, M.; Bagg, E.A.L.; Aik, W.S.; Krylova, S.M.; Ma, J.H.Y.; Chan, M.C.; Walport, L.J.; Wegman, D.W.; Dack, K.N.; McDonough, M.A.; Krylov, S.N.; Schofield, C.J. Dynamic combinatorial mass spectrometry leads to inhibitors of a 2-oxoglutarate dependent nucleic acid demethylase. Journal of Medicinal Chemistry 2012, 55, 2173–2184. (PDF file)

103. Dodgson, B.J.; Krylov, S.N. Time-resolved detection of luminescence for electrophoretic methods. Trends in Analytical Chemistry 2012, 33, 23–34. (PDF file)

102. Kanoatov, M.; Retif, C.; Cherney, L.T.; Krylov, S.N. Peak-shape correction to symmetry for pressure-driven sample injection in capillary electrophoresis. Analytical Chemistry 2012, 84, 149–154. (PDF file)

101. de Jong, S.; Krylov, S.N. Pressure-based approach for the analysis of protein adsorption in capillary electrophoresis. Analytical Chemistry 2012, 84, 453–458. (PDF file)

2011

100. Bao, J.; Krylova, S.M.; Reinstein, O.; Johnson, P.E.; Krylov, S.N. Label-free solution-based kinetic study of aptamer-small molecule interactions by kinetic capillary electrophoresis with UV detection revealing how kinetics control equilibrium. Analytical Chemistry 2011, 83, 8387–8390. (PDF file)

99. Cherney, L.T.; Kanoatov, M.; Krylov, S.N. Method for determination of peak areas in nonequilibrium capillary electrophoresis of equilibrium mixtures. Analytical Chemistry 2011, 83,  8617–8622. (PDF file)

98. Bao, J.; Krylova, S.M., Wilson, D.J.; Reinstein, O.; Johnson, P.E.; Krylov, S.N. Kinetic capillary electrophoresis with mass-spectrometry detection (KCE-MS) facilitates label-free solution-based kinetic analysis of protein-small molecule binding. ChemBioChem 2011, 12, 2551–2554. (DOI)

97. Okhonin, V.; Petrov, A.P.; Krylova, S.M.; Krylov, S.N. Quantitative characterization of micromixing based on uniformity and overlap. Angewandte Chemie International Edition 2011, 50, 11999–12002. (DOI)

96. Kanoatov, M.; Krylov, S.N. DNA adsorption to the reservoir walls causes irreproducibility in studies of protein-DNA interactions by methods of kinetic capillary electrophoresis. Analytical Chemistry 2011, 83, 8041–8045. (PDF file)

95. Wegman, D.W.; Krylov, S.N. Direct quantitative analysis of multiple miRNAs (DQAMmiR). Angewandte Chemie International Edition 2011, 50, 10335–10339. (PDF file)

94. Krylova, S.M.; Dove, P.M.; Kanoatov, M.; Krylov, S.N. The slow-dissociation and slow-recombination assumptions in non-equilibrium capillary electrophoresis of equilibrium mixtures. Analytical Chemistry 2011, 83, 7582–7585. (PDF file)

93. de Jong, S.; Krylov, S.N. Protein labeling enhances aptamer selection by methods of kinetic capillary electrophoresis. Analytical Chemistry 2011, 83, 6330–6335. (PDF file)

92. Petrov, A.P.; Cherney, L.T.; Dodgson, B.; Okhonin, V.; Krylov, S.N. Separation-based approach to study dissociation kinetics of non-covalent DNA-multiple protein complexes. Journal of the American Chemical Society 2011, 133, 12486–12492. (PDF file)

91. Koshkin, V.; Krylov, S.N. Single-cell-kinetics approach to compare multidrug resistance-associated membrane transport in subpopulations of cells. Analytical Chemistry 2011, 83, 6132–6134. (PDF file)

90. Petrov, A.P.; Dodgson, B.J.; Cherney, L.T.; Krylov, S.N. Predictive measure of quality of micromixing. Chemical Communications 2011, 47, 7767–7769. (PDF file)

89. Krylova, S.M.; Karkhanina, A.A.; Musheev, M.U.; Bagg, E.A.L.; Schofield, C.J.; Krylov, S.N. DNA aptamers for as analytical tools for the quantitative analysis of DNA-dealkylating enzymes. Analytical Biochemistry 2011, 414, 261–265. (PDF file)

88. Evenhuis, C.J.; Musheev, M.U.; Krylov, S.N. Universal method for determining electrolyte temperatures in capillary electrophoresis. Analytical Chemistry 2011, 83, 1808–1814. (PDF file)

87. Cherney, L.T.; Krylov, S.N. Slow-equilibration approximation in macroscopic approach to studying kinetics at equilibrium. Analytical Chemistry 2011, 83, 1381–1397. (PDF file)

86. Kanoatov, M.; Javaherian, S.; Krylov, S.N. Aptamer-facilitated protein isolation from cells. Nature Protocols/ProtocolExchange 2011, 204. (PDF file)

85. Agostino, F.J.; Evenhuis, C.J.; Krylov, S.N. Milli-free flow electrophoresis (mFFE): I. Fast prototyping of mFFE devices. Journal of Separation Science 2011, 34, 556–564. (PDF file)

2010

84. Kanoatov, M.; Javaherian, S.; Krylov, S.N. Selection of aptamers for a non-DNA binding protein in the context of cell lysate. Analytica Chimica Acta 2010, 681, 92–97. (PDF file)

83. Musheev, M.U.; Filiptsev, Y.; Okhonin, V.; Krylov, S.N. Electric field destabilizes noncovalent protein-DNA complexes. Journal of the American Chemical Society 2010, 132, 13639–13641. (PDF file)

82. Evenhuis, C.J.; Musheev, M.U.; Krylov, S.N. Heat-associated field distortion (HAFD) in electro-migration techniques. Analytical Chemistry 2010, 82, 8398–8401. (PDF file)

81. Musheev, M.U.; Filiptsev, Y.; Krylov, S.N. Temperature difference between the cooled and the noncooled parts of an electrolyte in capillary electrophoresis. Analytical Chemistry 2010, 82, 8692–8695. (PDF file)

80. Musheev, M.U.; Filiptsev, Y.; Krylov, S.N. Noncooled capillary inlet: a source of systematic errors in capillary electrophoresis-based affinity analyses. Analytical Chemistry 2010, 82, 8637–8641. (PDF file)

79. Evenhuis, C.J.; Okhonin, V; Krylov, S.N. Non-orthogonal micro-free flow electrophoresis: from theory to design. Analytica Chimica Acta 2010, 674, 102–109. (PDF file)

78. Okhonin, V; Berezovski, M.; Krylov, S.N. MASKE: macroscopic approach to studying kinetics at equilibrium. Journal of the American Chemical Society  2010, 132, 7062–7068. (PDF file)

77. Krylova, S.M.; Wegman, D.; Krylov, S.N. Making DNA hybridization assays in capillary electrophoresis quantitative. Analytical Chemistry  2010, 82, 4428–4433. (PDF file)

76. Okhonin, V.; Evenhuis, C.J.; Krylov, S.N. Non-orthogonal-to-the-flow electric field improves resolution in the orthogonal direction: hidden reserves for combining synthesis and purification in continuous flow. Analytical Chemistry 2010, 82, 1183–1185. (PDF file)

2009

75. Karkhanina, A.A.; Mecinovic,J.; Musheev, M.U.; Krylova, S.M. Petrov, A.P.; Hewitson, K.S.; Flashman, E.; Schofield, C.J.; Krylov, S.N. Direct analysis of enzyme-catalyzed DNA demethylation. Analytical Chemistry 2009, 81, 5871–5875. (PDF file)

74. Krylova, S.M.; Okhonin, V.; Evenhuis, C.J.; Krylov, S.N. The Inject-Mix-React-Separate-and-Quantitate (IMReSQ) approach to studying reactions in capillaries. Trends in Analytical Chemistry 2009, 28, 987–1010. (PDF file)

73. Javaherian, S.; Musheev, M.U.; Kanoatov, M.; Berezovski, M.; Krylov, S.N. Selection of aptamers for a protein target in cell lysate and their application to protein purification. Nucleic Acids Research 2009, 37, e62. (PDF file)

72. Krylova, S.M.; Okhonin, V.; Krylov, S.N. Transverse diffusion of laminar flow profiles - a generic method for mixing reactants in capillary microreactor. Journal of Separation Science 2009, 32, 742–756. (PDF file)

71. Drabovich, A.P.; Berezovski, M.; Musheev, M.U.; Krylov, S.N. Selection of smart small-molecule ligands: the proof of principle. Analytical Chemistry 2009, 81, 490–494. (PDF file)

70. Yunusov, D.; So, M.; Shayan, S.; Okhonin, V.; Musheev, M.U.; Berezovski, M.V.; Krylov, S.N. Kinetc capillary electrophoresis-based affinity screening of aptamer clones. Analytica Chimica Acta 2009, 631, 102–107. (PDF file)

2008

69. Wong, E.; Okhonin, V.; Berezovski, M.V.; Nozaki, T.; Waldmann, H.; Alexandrov, K.; Krylov, S.N. "Inject-Mix-React-Separate-and-Quantitate" (IMReSQ) method for screening of eznyme inhibitors. Journal of the American Chemical Society 2008, 130, 11862–11863. (PDF file)

68. Okhonin, V.; Wong, E.; Krylov, S.N. Mathematical model for mixing reactants in a capillary microreactor by transverse diffusion of laminar flow profiles. Analytical Chemistry 2008, 80, 7482–7486. (PDF file)

67. Musheev, M.U.; Javaherian, S.; Okhonin, V.; Krylov, S.N. Diffusion as a tool of measuring temperature inside a capillary. Analytical Chemistry 2008, 80, 6752–6757. (PDF file)

66. Berezovski, M.V.; Lechmann, M.; Musheev, M.U.; Mak, T.W.; Krylov, S.N. Aptamer-facilitated biomarker discovery (AptaBiD). Journal of the American Chemical Society 2008, 130, 9137–9143. (PDF file)

2007

65. Drabovich, A.P.; Okhonin, V.; Berezovski, M.; Krylov, S.N. Smart aptamers facilitate multi-probe affinity analysis of proteins with ultra-wide dynamic range. Journal of the American Chemical Society 2007, 129, 7260–7261. (PDF file)

64. Krylov, S.N. Kinetic CE: foundation for homogeneous kinetic affinity methods. Electrophoresis 2007, 28, 69–88. (PDF file)

63. Liu, Z.; Drabovich, A.P.; Krylov, S.N.; Pawliszyn, J. Dynamic kinetic capillary isoelectric focusing: new insights into protein-DNA interactions. Analytical Chemistry 2007, 79, 1097–1100. (PDF file)

62. Larijani, M.; Petrov, A.P.; Krylov, S.N.; Martin, A. AID is a sequence-independent single-stranded DNA binding protein: preferential mutation of hot-spot motifs is imposed during catalysis. Molecular and Cellular Biology 2007, 27, 20–30. (PDF file)

61. Berezovski, M.V.; Mak, T.W.; Krylov, S.N. Cell lysis inside the capillary facilitated by transverse diffusion of laminar flow profiles (TDLFP). Analytical and Bioanalytical Chemistry 2007, 387, 91–96. (PDF file)

2006

60. Berezovski, M.; Musheev, M.U.; Drabovich, A.P.; Jitkova, J.V.; Krylov, S.N. Non-SELEX: selection of aptamers without intermediate amplification of candidate oligonucleotides. Nature Protocols 2006, 1, 1359–1369. (PDF file)

59. Woolley, G.A.; Jaikaran, A.; Berezovski, M.; Calarco, J.D.; Krylov, S.N.; Smart, O.S.; Kumita, J.R. Reversible photo-control of DNA binding by a designed GCN4-bZIP protein. Biochemistry 2006, 45, 6075–6084. (PDF file)

58. Drabovich, A.P.; Berezovski, M.; Okhonin, V.; Krylov, S.N. Selection of smart aptamers by methods of kinetic capillary electrophoresis. Analytical Chemistry 2006, 78, 3171–3178. (PDF file)

57. Okhonin, V.; Petrov, A.; Berezovski, M.; Krylov, S.N. Plug-plug kinetic capillary electrophoresis: a method for direct determination of rate constants of complex formation and dissociation. Analytical Chemistry 2006, 78, 4803–4810. (PDF file)

56. Berezovski, M.; Musheev, M.; Drabovich, A.; Krylov, S.N. Non-SELEX selection of aptamers. Journal of the American Chemical Society 2006, 128, 1410–1411. (PDF file)

55. Drabovich, A.P.; Krylov, S.N. Identification of base pairs in single nucleotide polymorphisms by MutS protein-mediated capillary electrophoresis. Analytical Chemistry 2006, 78, 2035–2038. (PDF file)

54. Pang, Z.; Al-Mahrouki, A.; Berezovski, M.; Krylov, S.N. Selection of surfactants for cell lysis in chemical cytometry to study protein-DNA interactions. Electrophoresis 2006, 27, 1489–1494. (PDF file)

53. Krylov, S.N. Non-equilibrium capillary electrophoresis of equilibrium mixtures (NECEEM): a novel method for biomolecular screening. Journal of Biomolecular Screening 2006, 11, 115–122. (PDF file)

52. Musheev, M.U.; Krylov, S.N. Selection of aptamers by systematic evolution of ligands by exponential enrichment: addressing the polymerase chain reaction issue. Analytica Chimica Acta 2006, 564, 91–96. (PDF file)

2005

51. Petrov, A.; Okhonin, V.; Berezovski, M.; Krylov, S.N. Kinetic capillary electrophoresis (KCE): a conceptual platform for kinetic homogeneous affinity methods. Journal of the American Chemical Society 2005, 127, 17104–17110. (PDF file)

50. Al-Mahrouki, A.A.; Krylov, S.N. Calibration-free quantitative analysis of messenger RNA. Analytical Chemistry 2005, 77, 8027–8030. (PDF file)

49. Okhonin, V.; Liu, X.; Krylov, S.N. Transverse diffusion of laminar flow profiles to produce capillary nanoreactors. Analytical Chemistry 2005, 77, 5925-5929. (PDF file)

48. Drabovich, A.; Berezovski, M.; Krylov, S.N. Selection of smart aptamers by equilibrium capillary electrophoresis of equilibrium mixtures (ECEEM). Journal of the American Chemical Society 2005, 127, 11224–11225. (PDF file)

47. Krylova, S.M.; Musheev, M.; Nutiu, R.; Li, Y. Lee, G.; Krylov, S.N. Tau protein binds single-stranded DNA sequence specifically - the proof obtained in vitro with non-equilibrium capillary electrophoresis of equilibrium mixtures. FEBS Letters 2005, 579, 1371–1375. (PDF file)

46. Berezovski, M.; Drabovich, A.; Krylova, S.M.; Musheev, M.; Okhonin, V.; Petrov, A.; Krylov, S.N. Nonequilibrium capillary electrophoresis of equilibrium mixtures: a universal tool for development of aptamers. Journal of the American Chemical Society 2005, 127, 3165–3171. (PDF file)

45. Berezovski, M.; Krylov, S.N. Thermochemistry of protein-DNA interaction studied with temperature-controlled nonequilibrium capillary electrophoresis of equilibrium mixtures. Analytical Chemistry 2005, 77, 1526–1529. (PDF file)

44. Arkhipov, S.N.; Berezovski, M.; Jitkova, J.; Krylov, S.N. Chemical cytometry for monitoring metabolism of a Ras-mimicking substrate in single cells. Cytometry 2005, 63A, 41–47. (PDF file)

2004

43. Berezovski, M.; Krylov, S.N. Using nonequilibrium capillary electrophoresis of equilibrium mixtures for the determination of temperature in capillary electrophoresis. Analytical Chemistry 2004, 76, 7114–7117.  (PDF file)

42. Krylova, S.M.; Rozenberg, D.; Coulton, J.W.; Krylov, S.N. Monitoring viral DNA release with capillary electrophoresis. Analyst 2004, 129, 1234–1237.  (PDF file)

41. Drabovich, A.; Krylov, S.N. Single-stranded DNA-binding protein facilitates gel-free analysis of polymerase chain reaction products in capillary electrophoresis. Journal of Chromatography A 2004, 1051, 171–175. (PDF file)

40. Jitkova, J.; Carrigan, C.N; Poulter, C.D.; Krylov, S.N.  Monitoring the three enzymatic activities involved in posttranslational modifications of Ras proteins.  Analytica Chimica Acta  2004, 521, 1–7. (PDF file)

39. Hu, K.; Ahmadzadeh, H.; Krylov, S.N. Asymmetry between sister cells in a cancer cell line revealed by chemical cytometry. Analytical Chemistry 2004, 76, 3864–3866. (PDF file)

38. Okhonin, V.; Berezovski, M.; Krylov, S.N. Sweeping capillary electrophoresis: a non-stopped-flow method for measuring bimolecular rate constant of complex formation between protein and DNA. Journal of the American Chemical Society 2004, 126, 7166–7167.  (PDF file)

37. Okhonin, V.; Krylova, S.M.; Krylov, S.N. Nonequilibrium capillary electrophoresis of equilibrium mixtures, mathematical model.  Analytical Chemistry 2004, 76, 1507–1512. (PDF file)

36. Hu, K.; Zarrine-Afsar, A.; Ahmadzadeh, H.; Krylov, S.N. Single-cell analysis by chemical cytometry combined with fluorescence microscopy. Instrumentation Science and Technology 2004, 32, 31–41. (PDF file)

2003

35. Berezovski, M.; Krylov, S.N. Using DNA-binding proteins as an analytical tool. Journal of the American Chemical Society 2003, 125, 13451–13454. (PDF file)

34. Zarrine-Afsar, A.; Krylov, S. N. Use of capillary electrophoresis and endogenous fluorescent substrate to monitore intracellular activation of protein kinase A. Analytical Chemistry 2003, 75, 3720–3724. (PDF file)

33. Hu, S.; Zhang, L.; Krylov, S.; Dovichi, N.J. Cell-cycle dependent protein fingerprint from a single cancer cell: image cytometry coupled with single-cell capillary sieving electrophoresis. Analytical Chemistry 2003, 75, 3495–3501. (PDF file)

32. Krylov, S. N.; Berezovski, M. Non-equilibrium capillary electrophoresis of equilibrium mixtures - appreciation of kinetics in capillary electrophoresis. Analyst 2003, 128, 571–575. (PDF file)

31. Berezovski, M.; Nutiu, R.; Li, Y.; Krylov, S.N. Affinity analysis of a protein-aptamer complex using nonequilibrium capillary electrophoresis of equilibrium mixtures. Analytical Chemistry 2003, 75, 1382–1386. (PDF file)

2002

30. Berezovski, M.; Krylov, S.N. Nonequilibrium capillary electrophoresis of equilibrium mixtures - a single experiment reveals equilibrium and kinetic parameters of protein-DNA interactions. Journal of the American Chemical Society 2002, 124, 13674–13675. (PDF file)

29. Stoyanov, A.V.; Ahmadzadeh, H.; Krylov, S.N. Heterogeneity of protein labeling with a fluorogenic reagent, 3-(2-furoyl)quinoline-2-carboxaldehyde. Journal of Chromatography B 2002, 780, 283–287. (PDF file)

28. Berezovski, M.; Li, W.-P.; Poulter, C.D.; Krylov, S.N. Measuring the activity of farnesyltransferase by capillary electrophoresis with laser-induced fluorescence detection. Electrophoresis 2002, 23, 3398–3403. (PDF file)

2001

27. Hu, S.; Lee, R.; Zhang, Z.; Krylov, S.N.; Dovichi, N.J. Protein analysis of an individual Caenorhabditis elegans single-cell embryo by capillary electrophoresis. Journal of Chromatography B 2001, 752, 307–310. (PDF file)

2000

26. Zhang, L.; Krylov, S.N.;  Hu, S.; Dovichi, N. Methyl-beta-cyclodextrin modified micellar electrokinetic capillary chromatography with laser-induced fluorescence for separation and detection of phospholipids. Journal of Chromatography A 2000, 894, 129–134. (PDF file)

25. Krylov, S.N.; Arriaga, E.A.; Chan, N.W.C.; Dovichi, N.J.; Palcic, M.M. Metabolic cytometry: monitoring oligosaccharide biosynthesis in single cells by capillary electrophoresis. Analytical Biochemistry 2000, 283, 133–135. (PDF file)

24. Krylov, S.N.; Dovichi, N.J. Capillary electrophoresis for the analysis of biopolymers. Analytical Chemistry 2000, 72, 111R–128R. (PDF file)

23. Krylov, S.N.; Starke, D.A.; Arriaga, E.; Chan, N.W.C.; Zhang, Z.; Palcic, M.M., Dovichi, N.J. Instrumentation for chemical cytometry. Analytical Chemistry 2000, 72, 872–877. (PDF file)

22. Krylov, S.N.; Dovichi, N.J. Single-cell analysis using capillary electrophoresis: influence of surface support properties on cell injection into the capillary. Electrophoresis 2000, 21, 767–773. (PDF file)

21. Krylov, S.N.; Arriaga, E.; Zhang, Z.; Chan, N.W.C.; Palcic, M.M.; Dovichi, N.J. Single-cell analysis avoids sample processing bias. Journal of Chromatography B 2000, 741, 31–35. (PDF file)

20. Zhang, Z.; Krylov, S.N.; Arriaga, E.; Dovichi, N.J. One-dimentional protein map of an HT29 human colon adenocarcinoma cell. Analytical Chemistry 2000, 72, 318–322. (PDF file)

1999

19. Krylov, S.N.; Arriaga, E.; Zhang, Z.; Chan, N.W.C.; Palcic, M.M.; Dovichi, N.J. Correlating cell cycle with metabolism in single cells: the combination of image and metabolic cytometry. Cytometry 1999, 37, 14–20. (PDF file)

1998

18. Krylov, S.N. Computer simulation of damped oscillations during peroxidase-catalyzed oxidation of indole-3-acetic acid. Biophysical Chemistry 1998, 72, 285–297. (PDF file)

1997

17. Krylov, S.N.; Huang, X.-D.; Zeiler, L.F.; Dixon, D.G.; Greenberg, B.M. Mechanistic quantitative structure-activity relationship model for the photoinduced toxicity of polycyclic aromatic hydrocarbons: I. Physical model based on chemical kinetics in a two-compartment system. Environmental Toxicology and Chemistry 1997, 16, 2283–2295. (PDF file)

16. Huang, X.-D.; Krylov, S.N.; Ren, L.; McConkey, B.J.; Dixon, D.G.; Greenberg, B.M. Mechanistic quantitative structure-activity relationship model for the photoinduced toxicity of polycyclic aromatic hydrocarbons: II. An empirical model for the toxicity of 16 polycyclic aromatic hydrocarbons to the duckweed Lemna gibba L. G-3. Environmental Toxicology and Chemistry 1997, 16, 2296–2303. (PDF file)

1996

15. Krylov, S.N.; Dunford, H.B. Accelerating effect of umbelliferone on peroxidase-catalyzed oxidation of indole-3-acetic acid at neutral pH. Journal of Physical Chemistry 1996, 100, 19719–19727. (PDF file)

14. Krylov, S.N.; Dunford, H.B. Detailed mechanism of phenol-inhibited peroxidase-catalyzed oxidation of indole-3-acetic acid. Photochemistry and Photobiology 1996, 63, 735–741. (PDF file)

13. Krylov, S.N.; Krylova, S.M. Optically pumped chemiluminescence of indole-3-acetic acid. Photochemistry and Photobiology 1996, 63, 621–627. (PDF file)

12. Krylov, S.N.; Dunford, H.B. Detailed model of peroxidase-catalyzed oxidation of indole-3-acetic acid at neutral pH. Journal of Physical Chemistry 1996, 100, 913–920. (PDF file)

11. Krylov, S.N.; Dunford, H.B. Evidence for a free chain mechanism in the reaction between peroxidase and indole-3-acetic acid at neutral pH. Biophysical Chemistry 1996, 58, 325–334. (PDF file)

1995

10. Krylov, S.N.; Aguda, B.D.; Ljubimova, M.L. Bistability and reaction thresholds in the phenol-inhibited peroxidase-catalyzed oxidation of indole-3-acetic acid. Biophysical Chemistry 1995, 53, 213–218. (PDF file)

1994

9. Krylov, S.N.; Krylova, S.M.; Chebotarev, I.G.; Chebotareva, A.B. Inhibition of enzymatic indole-3-acetic acid oxidation by phenols. Phytochemistry 1994, 36, 263–267. (PDF file)

8. Krylov, S.N.; Chebotareva, A.B. Effect of xanthene dyes on peroxidase-catalyzed oxidation of indole-3-acetic acid. Biochemistry (Moscow) 1994, 59, 499–503. (PDF file)

1993

7. Krylov, S.N.; Chebotareva, A.B. Peroxidase-catalyzed co-oxidation of indole-3-acetic acid and xanthene dyes in the absence of hydrogen peroxide. FEBS Letters 1993, 324, 6–8. (PDF file)

6. Krylov, S.N.; Krylova, S.M.; Rubin, L.B. Threshold effect during inhibition by caffeic acid of peroxidase-catalyzed oxidation of indole-3-acetic acid. Biophysics (Translated from Biofizika) 1993, 38, 399–403. (PDF file)

5. Krylov, S.N.; Krylova, S.M.; Rubin, L.B. Threshold effect of caffeic acid on peroxidase-catalyzed oxidation of indole-3-acetic acid. Phytochemistry 1993, 33, 9–12. (PDF file)

4. Krylov, S.N.; Krylova, S.M.; Rubin, L.B. Mechanism of inhibition of enzymatic oxidation of indole-3-acetic acid by phenols. Biochemistry (Moscow) 1993, 58, 660–666. (PDF file)

1992

3. Kosolobova, E.V.; Krylov, S.N.; Lazarev, V.V.; Ljubimova, M.L.; Rubin, L.B. Mathematical model of bistability in the peroxidase-oxidase reaction under the effect of free radical traps. Doklady Biophysics (translated from the Proceeding of the Russian Academy of Sciences) 1992, 326, 81–84. (PDF file)

2. Krylov, S.N.; Krylova, S.M.; Rubin, L.B. Bistability in enzymatic oxidation of heteroauxin with inhibition by caffeic acid. Doklady Biophysics (translated from the Proceeding of the Russian Acadeny of Sciences) 1992, 326, 73–77. (PDF file)

1990

1. Krylov, S.N.; Lazarev, V.V.; Rubin, L.B. Kinetics associated with chemiluminescence spectra during the oxidation of heteroauxin by peroxidase. Doklady Biophysics (translated from the Proceeding of the Russian Acadeny of Sciences) 1990, 310, 28–31. (PDF file)

Publications - Refereed Conference Proceedings

  • Berezovski, M.; Okhonin, V.; Petrov, A.; S.N. Krylov. Kinetic methods in capillary electrophoresis and their applications. Proceeding of the International Society for Optical Engineering 2005, 5969, 203–215.
  • Hu, S.; Krylov, S.; Zhang, L.; Zhang, Z.; Lee, R.; Dovichi, N. Molecular cytometry: analysis of proteins in single cells. Proceeding of the International Society for Optical Engineering 2002, 4625, 98–105.
  • Krylov, S.N.; Zhang, Z.; Dovichi, N.J. Metabolic cytometry. In: Scanning And Force Microscopies For Biomedical Applications II. (Eds.: Nie, S.; Tamiya, E.; Yeung, E.S.) Proceedings of SPIE 2000, 3922, 73–81.

Publications - Book Chapters

  • Krylov, S.N. Kinetic capillary electrophoresis for selection, characterization, and analytical utilization of aptamers. In: Aptamers in bioanalysis (Ed. Mascini, M.) Wiley, 2009, 183–212.
  • Berezovski, M.; Krylov, S.N. Kinetic capillary electrophoresis. In: Capillary and microchip electrophoresis and associated microtechniques (Ed. Landers, J.P.) CRC Press, N.Y., 2008, pp.361–380.
  • Ahmadzadeh, H; Krylov, S.N. On-column labeling reaction for analysis of a single cell using capillary electrophoresis. In: Capillary electrophoresis of peptides and proteins (Eds.: Strege, M.; Lagu, A.L.), Humana Press, Totowa, New Jersey, 2004, pp. 29–38.
  • Ahmadzadeh, H; Dovichi, N.J.; Krylov, S.N. Capillary coating for protein separation based on Si-O and Si-C covalent bond formation for capillary electrophoresis with laser-induced fluorescence detection (Eds.: Strege, M.; Lagu, A.L.), Humana Press, Totowa, New Jersey, 2004, pp. 15–27.
  • Hu, S.; Michels, D.; Zhang, Z.; Krylov, S.N.; Dovichi, N.J. Proteome analysis by capillary electrophoresis. In: Biotechnology 2nd Edition, Volume 5b Genomics and Bioinformatics (Ed.: Sensen, C.) Wiley-VCH, Weinheim, 2001, pp. 269–278.
  • Krylov, S.N.; Arriaga, E.; Chan, N.W.C.; Dovichi, N.J.; Palcic, M.M. Metabolic cytometry: monitoring oligosaccharide biosynthesis in single cells. In: Sialobiology and other forms of glycosylation (Eds.: Inoue, Y.; Lee, Y.C.; Troy II, F.A.), Gakushin Publishing, Osaka, 1999, pp. 259–264.
  • Krylov, S.N.; Dunford, H.B. Reaction of horseradish peroxidase with indole-3-acetic acid. In: Plant peroxidases: biochemistry and physiology (Eds.: Obinger, C.; Burner, U. Ebermann, R.; Penel, C.; Greppin, H.), University of Geneva, 1996, pp. 59–69.

Publications - Book Reviews

  • Krylov, S.N.  Review on the book: Probes and Tags to Study Biomolecuar Function for Proteins, RNA, and Membranes (Ed.: Miller, L.) Journal of the American Chemical Society 2009, 131, 1621–1622. (PDF file)
  • Krylov, S.N. Separation helps (Review on the book: Cell separation, A practical approach. Eds.: Fisher, D.; Francis, G.E.; Rickwood, D.). Trends in Cell Biology 1999, 9, 462–463. (PDF file)